Publications by authors named "Lin-feng Lu"
Article Synopsis
- Gut microbiota dysbiosis plays a significant role in depression, and Hypericum perforatum L. (HPL) has been traditionally used in Europe to treat this condition, though its mechanisms remain unclear.
- The study investigates how HPL affects gut microbiota and related metabolites to alleviate depression symptoms, utilizing fecal microbiota transplantation and advanced microbiome profiling methods.
- Results show that HPL improves depression by restoring beneficial gut bacteria (like Akkermansia muciniphila) and regulating tryptophan metabolism, influencing inflammatory pathways related to mood disorders.
Objective: To investigate the inhibition of sanguinarine on S180 sarcoma in mice and the effect of angiogenesis.
Methods: S180 subcutaneous implanted tumor model mice were randomly divided into six groups: control group, cyclophosphamide (CTX) group, sanguinarine (10, 20 and 40 mg/kg) groups and combination group. The mice were sacrificed on the 10th day to measure the tumor weight and volumes, and caculate the tumor growth inhibition.
It is relatively difficult to diagnose bacterial sepsis in nephrolithiasis patients. The aim of the study is to evaluate the diagnostic ability of presepsin in the differential diagnosis including SIRS, infection, or sepsis and to compare its diagnostic value with other markers, mainly as CRP, procalcitonin (PCT), and white blood cell (WBC) in patients of nephrolithiasis presenting with SIRS. 39 patients of nephrolithiasis who were diagnosed as SIRS were prospectively investigated.
View Article and Find Full Text PDF