Distributed source modeling of stereoencephalographic measurements of ictal activity.

Objectives: Stereoelectroencephalography (SEEG) can define the epileptogenic zone (EZ). However, SEEG is susceptible to the sampling bias, where no SEEG recording is taken within a circumscribed EZ.

Methods: Nine patients with medically refractory epilepsy underwent SEEG recording, and brain resection got positive outcomes.