Stepwise construction of a metallocatenane based on non-labile bis(terpyridine)-Cd complexes.

A series of metalloligands bearing homoleptic 2,2':6',2''-terpyridine (tpy)-Cd complexes has been successfully synthesized. The formation of ML was accomplished through a sequence of Suzuki-Miyaura coupling and complexation reactions, offering an alternative method to produce tpy-based metalloligands under relatively mild conditions. Moreover, the metallomacrocycle C and metallocatenane C were self-assembled from heteroleptic complexation reactions involving ML and suitable counterparts.

Multicomponent Metallo-Supramolecular Nanocapsules Assembled from Calix[4]resorcinarene-Based Terpyridine Ligands.

Tetrafunctionalized calix[4]resorcinarene cavitands commonly serve as supramolecular scaffolds for construction of coordination-driven self-assembled capsules. However, due to the calix-like shape, the structural diversity of assemblies is mostly restricted to dimeric and hexameric capsules. Previously, we reported a spontaneous heteroleptic complexation strategy based on a pair of self-recognizable terpyridine-based ligands and Cd ions.

Construction and interconversion of anion-coordination-based ('aniono') grids and double helicates modulated by counter-cations.

Supramolecular assembly of well-defined discrete architectures has been of great interest due to the tunable properties of these structures in functional materials and bio-mimicking. While metal-coordination-driven assembly has been extensively studied, anion-coordination-driven assembly (ACDA) is just emerging for constructing complex supramolecular structures. Herein two A (A = anion, = ligand; = 1 or 2) 'aniono'-supramolecular assemblies, double helicates and the first anion grid, have been constructed based on the coordination between phosphate (PO ) anion and a bis-tris(urea) ligand.

A concise approach to the synthesis of the unique N-mannosyl d-β-hydroxyenduracididine moiety in the mannopeptimycin series of natural products.

The asymmetric synthesis of the orthogonally protected N-mannosyl d-β-hydroxyenduracididine (N-Man-d-βhEnd) is described, starting from enantiopure silylated (S)-serinol. The key steps are: (i) glycosylamine formation between protected serinol and a benzylated d-mannose; (ii) guanidinylation; and (iii) cyclic guanidine formation. This synthesis constitutes a breakthrough in our studies towards a total synthesis of mannopeptimycin and should also allow for other studies in the field of mannopeptimycin research, including the synthesis of derivatives.