[Gender-dependent Expression of ERβ in AEC Ⅱ of Fetal Mice Exposed to Arsenic and Estrogen Receptor Antagonist].

Objective: To determine the effects of arsenic and estrogen receptor antagonist (ICI182, 780) on the expression of estrogen receptor beta (ERβ) in alveolar Ⅱ epithelial cells (AECⅡ) of female and male mice.

Methods: Nineteen or twenty day fetus mice were obtained through caesarean section of ICR mice. Purified AECⅡ cells were separated from the female and male fetus,respectively,and confirmed using immunofluorescence staining.

[The Relationship of Polymorphisms in Interleukin 17A Gene, Interleukin 17F Gene and the Pulmonary Inflammation Risk in Dust Exposed Workers in a Chinese Population].

Objectives: To investigate the polymorphisms in interleukin 17A and interleukin 17F () and their relationship with pulmonary inflammation risk of dust exposed workers.

Methods: A case-control study among 193 subjects, including 67 subjects in case group and 126 in control group was conducted. PCR-RFLP was applied to genotype (G-197A) and (7488T/C).