Publications by authors named "Lin-Lin Cui"
Article Synopsis
- Microorganisms, like the bacterium 'Aliisedimentitalea scapharcae' KCTC 42119 found in marine animals, can produce valuable bioactive substances such as antibiotics to help them compete for resources.* -
- The complete genome sequencing revealed that this bacterium has a large genome of 5,083,900 bp with nine biosynthetic gene clusters, indicating its potential to produce medicinal substances.* -
- The identified secondary metabolites include antibiotics and cytoprotective compounds, highlighting the promise of this strain for pharmaceutical applications and the potential for further exploration of animal-associated microorganisms for bioactive substances.*
Toxoplasma gondii is an important protozoan pathogen, which can cause severe diseases in the newborns and immunocompromised individuals. Developing an effective vaccine against Toxoplasma infection is a critically important global health priority. Immunofluorescence staining analysis revealed that TgSAG2 and TgSRS2 are membrane associated and displayed on the surface of the parasite.
View Article and Find Full Text PDFThe frequency of exertional heat stroke (EHS) increases with the gradual elevation of global temperatures during summer. Acute kidney injury (AKI) is a common complication of EHS, and its occurrence often indicates the worsening of a patient's condition or a poor prognosis. In this study, a rat model of AKI caused by EHS was established, and the reliability of the model was evaluated by HE staining and biochemical assays.
View Article and Find Full Text PDFThis work was performed to determine the pharmacological effects of Bufei Jianpi granules on chronic obstructive pulmonary disease and its metabolism in rats. Chronic obstructive pulmonary disease (COPD), ranked as the third leading cause of death worldwide, is seriously endangering human health. At present, the pathogenesis of COPD is complex and unclear, and the drug treatment mainly aims to alleviate and improve symptoms; however, they cannot achieve the purpose of eradicating the disease.
View Article and Find Full Text PDFGiardia duodenalis, an intestinal parasite, is widely distributed in humans and various animals, such as pigs, cattle and cats. The clinical symptoms of giardiasis are characterized as including abdominal pain, acute or chronic diarrhea, and bloating and weight loss in humans and animals, leading to public and veterinary health problems worldwide. However, the prevalence and genotypes of G.
View Article and Find Full Text PDFBackground: Toxoplasma gondii is an obligate intracellular parasite that causes toxoplasmosis. Urine is an easily obtained clinical sample that has been widely applied for diagnostic purposes. However, changes in the urinary proteome during T.
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- Prunella vulgaris has traditionally been used in Chinese medicine for treating liver cancer, but its current focus is mainly on thyroid and throat cancers; this paper aims to investigate its potential effectiveness against liver cancer specifically.
- The study examines the anti-cancer effects of Prunella vulgaris' total flavonoids using various methods, including cell analysis and testing in tumor-bearing mice.
- Results indicate that Prunella vulgaris total flavonoids can inhibit cancer cell proliferation, reduce tumor size, and enhance immune responses in treated mice, suggesting its potential as a therapeutic option for liver cancer.
Article Synopsis
- This study investigates the prevalence of parasitic species in pigs from southeastern China, focusing on their potential as zoonotic reservoirs for human infections.
- A total of 668 fecal samples were analyzed, revealing an overall infection rate of 55.4%, with the highest rates for ST1 (45.2%) and ST3 (34.1%).
- Coinfections were identified, including a 25.1% rate for ST1 and ST3, marking the first report of mixed infections and the molecular identification of these species in this region of China.
Enterocytozoon bieneusi is an important opportunistic pathogen widely distributed in humans and animals that causes diarrhea or fatal diarrhea in immunocompromised hosts. To examine the infection status and molecular characteristics of E. bieneusi in pigs, 725 fecal samples were collected from pigs in six areas of Fujian Province.
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