Publications by authors named "Lin-Juan Xu"
Article Synopsis
- Bone or brain metastases occur in 20-40% of late-stage non-small-cell lung cancer (NSCLC) patients, leading to a poor median survival of 4-6 months, yet the distinctions in metastatic types at the single-cell level remain underexplored.
- A comprehensive analysis of 14 biopsy samples from treatment-naïve advanced NSCLC patients revealed significant differences in cancer-associated fibroblast (CAF) populations among the bone, brain, and intrapulmonary metastases.
- The study highlights the role of specific CAF subpopulations in promoting either bone or brain metastasis and suggests potential therapeutic targets by disrupting their interactions with tumor cells to inhibit metastasis.
Locally advanced cervical rhabdomyosarcoma in adults: A case report.
World J Clin Cases
September 2022
Background: Rhabdomyosarcoma is a soft tissue tumor of primitive mesenchymal cells origin, occurring predominantly in children and adolescents, but extremely rare in adults and the data regarding its treatment are sparse. Here, we would like to share our experience in the treatment of a locally advanced primary embryonal rhabdomyosarcoma of cervix in a 39-year-old female.
Case Summary: The patient was admitted with symptoms of intermenstrual bleeding and postcoital bleeding for six months.