Publications by authors named "Lin-Jing Guan"
Article Synopsis
- Breast cancer (BC) is a complex disease, and new research is focusing on PANoptosis, a mechanism of programmed cell death, to understand its effects on patient prognosis and the immune environment surrounding tumors.
- The study analyzed gene expression data from large cancer databases to identify PANoptosis-related genes (PRGs) and develop a prognostic signature to categorize BC patients into low- and high-risk groups based on these genes.
- Findings revealed that patients in the low-risk group had better survival outcomes and that the proposed model could help predict patient prognosis, drug sensitivity, and the tumor's immune characteristics.
Global, regional, and national burden of gallbladder and biliary diseases from 1990 to 2019.
World J Gastrointest Surg
November 2023
Background: Gallbladder and biliary diseases (GABDs) are a major public health issue.
Aim: To analysis the cause-specific incidence, prevalence, and years lived with disability (YLDs) and its temporal trends of GABDs at the global, regional, and national level. Data on GABD were available from the Global Burden of Disease study 2019.
Objective: To investigate the influence of environment on the genetic structure and chemical ingredients of different Codonopsis species.
Methods: Amplified fragment length polymorphism( AFLP) molecular markers were used to analyze the genetic polymorphism of Codonopsis species from 24 different populations,and high performance liquid chromatography( HPLC) fingerprints were performed to analyze the chemical ingredients of 10 batches of Codonopsis roots.
Results: According to species classification,the 24 populations were categorized into three groups by UPGMA cluster method.
In this paper, the RP-HPLC specific chromatography was adopted, with DIKMA-C18 (4.6 mm x 250 mm, 5 µm) as the chromatographic column, with a gradient elution compose of acetonitrile and 0.1% phosphoric acid at flow rate of 0.
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