The impact of enterprise resilience and HRM practices on performance: Findings from fsQCA.

Background: Both enterprise resilience and HRM practices can have a positive impact on enterprise performance. The impact of enterprise resilience or human resource management (HRM) practices on enterprise performance independently has been studied widely. But few studies have combined the above two aspects to discuss their impact on enterprise performance.

Establishing and applying an adaptive strategy and approach to eliminating malaria: practice and lessons learnt from China from 2011 to 2020.

On 30 June 2021, China was certified malaria-free by the World Health Organization. In this study, the evolution, performance, outcomes, and impact of China's adaptive strategy and approach for malaria elimination from 2011 to 2020 were analysed using 10-year data. The strategy and approach focused on timely detection and rapid responses to individual cases and foci.

Quantitative Microbial Risk Assessment of and in Public Drinking Water in China.

We aimed to assess the risks of and infections associated with drinking water for local residents, based on a quantitative microbial risk assessment, in three densely populated regions of China. In total, 45 source water samples and 45 treated water samples were collected from June to December 2014. Five -positive samples and 5 -positive samples were found.

No evidence of amplified Plasmodium falciparum plasmepsin II gene copy number in an area with artemisinin-resistant malaria along the China-Myanmar border.

Background: The emergence and spread of artemisinin resistance in Plasmodium falciparum poses a threat to malaria eradication, including China's plan to eliminate malaria by 2020. Piperaquine (PPQ) resistance has emerged in Cambodia, compromising an important partner drug that is widely used in China in the form of dihydroartemisinin (DHA)-PPQ. Several mutations in a P.

Artemisinin resistance-associated markers in Plasmodium falciparum parasites from the China-Myanmar border: predicted structural stability of K13 propeller variants detected in a low-prevalence area.

Background: Malaria reduction and future elimination in China is made more difficult by the importation of cases from neighboring endemic countries, particularly Myanmar, Laos, and Vietnam, and increased travel to Africa by Chinese nationals. The increasing prevalence of artemisinin resistant parasites across Southeast Asia highlights the importance of monitoring the parasite importation into China. Artemisinin resistance in the Mekong region is associated with variants of genes encoding the K13 kelch domain protein (pf13k), found in specific genetic backgrounds, including certain alleles of genes encoding the chloroquine resistance transporter (pfcrt) and multidrug resistance transporter PgH1 (pfmdr1).

[Science and technology-led technical innovation provides a driving force to accelerate the progress of malaria elimination].

Since the malaria elimination program was launched, a series of scientific research programs have been conducted in Jiangsu Province, including epidemiology, pathogenic biology and vector biology, and some novel techniques and approaches have been established, which provides a strong safeguard for malaria elimination in Jiangsu Province and achieves the effective interruption of local malaria transmission. In addition, these tools provide new insights into and technical support for the national and global malaria elimination programs.

A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.

Background: Recent gains in reducing the global burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations in portions of a P. falciparum gene encoding kelch (K13)-propeller domains are the major determinant of resistance has provided opportunities for monitoring such resistance on a global scale.

[Opportunities, Challenges and Strategies for Malaria Elimination in the Tibet Autonomous Region of China].

This review summarizes the endemic characteristics and influencing factors of malaria in the Tibet Autonomous Region of China, as well as the opportunities and challenges for malaria elimination in this region. Recommendations on strategies for malaria control are also made.

[Establishment and Application of Multiplex PCR System for Detecting Four Human Plasmodium Species].

Objective: To establish a multiplex PCR detection system for identifying 4 human Plasmodium species and evaluate its applicability.

Methods: The sequences of 18S rDNA gene of the 4 human Plasmodium species were compared using DNAman software, and 4 downstream primers were designed using Oligo 6.0 software, which targeted the region of variability between conserved regions 5 and 6 of the sequences.

In vivo monitoring of dihydroartemisinin-piperaquine sensitivity in Plasmodium falciparum along the China-Myanmar border of Yunnan Province, China from 2007 to 2013.

Background: Artemisinin-based combination therapy (ACT) is the recommended first-line treatment of falciparum malaria in all endemic countries. Artemisinin resistance in Plasmodium falciparum has been confirmed in the Greater Mekong subregion (GMS). Dihydroartemisinin-piperaquine (DAPQ) is the most commonly used ACT in China.

Transition from control to elimination: impact of the 10-year global fund project on malaria control and elimination in China.

The Global Fund to Fight AIDS, Tuberculosis and Malaria (GFATM) supported a project on the control and elimination of malaria in People's Republic of China which was one of the biggest-scale international cooperation programmes to control malaria in the country during the past 10 years. The project promoted the effective implementation of the Chinese national malaria control programme. On the basis of epidemiologic data, an overview of the project activities and key performance indicators, the overall impact of the GFATM project was evaluated.

Lessons from malaria control to elimination: case study in Hainan and Yunnan provinces.

Reduction patterns of Plasmodium falciparum and P. vivax malaria transmission and the role of an integrated strategy of case management and vector control are compared between different ecological zones. The epidemiology of malaria in Hainan and Yunnan provinces was disparate, even though distinct malaria control strategies have been adapted to different situations based on risk group, vector behaviours, local health infrastructure, and environmental conditions.

Application of Auto-regressive Linear Model in Understanding the Effect of Climate on Malaria Vectors Dynamics in the Three Gorges Reservoir.

It is important to understand the dynamics of malaria vectors in implementing malaria control strategies. Six villages were selected from different sections in the Three Gorges Reservoir for exploring the relationship between the climatic factors and its malaria vector density from 1997 to 2007 using the auto-regressive linear model regression method. The result indicated that both temperature and precipitation were better modeled as quadratic rather than linearly related to the density of Anopheles sinensis.

Monitoring Plasmodium vivax chloroquine sensitivity along China-Myanmar border of Yunnan Province, China during 2008-2013.

Background: Plasmodium vivax is the most widespread of the malaria parasites infecting human hosts. In malaria-eliminating settings, both imported and local malaria predominantly occurs in border areas, and most of them are P. vivax.

[Overviews on Plasmodium ovale wallikeri and its genetic detection system].

In recent years, some microscopy-positive but nest-PCR negative (based on small subunit ribosomal RNA gene) ovale malaria cases were reported. The detection failure was due to the genetic variations between Plasomdoium ovale wallikeri and P. ovale curtisi.

[Preliminary application of moving percentile method on surveillance and early-warning on visceral leishmaniasis in endemic areas].

Objective: To apply moving percentile method on surveillance and early-warning on visceral leishmaniasis in Kashgar Region and evaluate its effect.

Methods: Incidence data of visceral leishmaniasis in Kashgar Region were collected from the National Web-based Infectious Diseases Report System. Monthly detection was carried out by using moving percentile method.

[Malaria from control to elimination in China: transition of goal, strategy and interventions].

The Malaria Elimination Action Plan has been launched in China since 2010, to pursue the goal of national wide malaria elimination by 2020. To ensure the achievement of the goal, the strategy and interventions should be transited from control to elimination, based on the better understanding of malaria elimination. In this article, we delineate the difference between malaria control and elimination phase, and explain the importance of transition of the goal, strategy and interventions from control to elimination, also decrypt the background, definition, critical points and challenges of China's current malaria elimination strategy and interventions, to improve health workers' understanding and implementation of national elimination program at different levels, and eventually impact the progress of national elimination program.

[Ecological behavior comparison between Anopheles pseudowillmori and A. willmori in villages with malaria outbreaks in Motuo County, Tibet Autonomous Region].

Objective: To understand the ecological behaviors of Anopheles pseudowillmori and A. willmori in medium or high altitude areas of Motuo County, Tibet Autonomous Region, and their transmission potential for malaria.

Methods: The methods of human net traps, cow baited trap, house baited trap, pig baited trap and CDC light traps were adopted for investigating the mosquito density, biting activity at night and in or out door preference of biting.

Application of structural equation models for elucidating the ecological drivers of Anopheles sinensis in the three gorges reservoir.

Objective: To identify the major ecological drivers for malaria vector density using the structural equation model (SEM) in the Three Gorges Reservoir.

Method: An 11-year longitudinal surveillance of malaria vector as well as its related ecological factors was carried out in the Three Gorges Reservoir. The Delphi method was used to identify associated ecological factors.

[Changes of pyrethroid resistance and P450 monooxygenase activity with age in Anopheles sinensis in Huainan City, Anhui Province, China].

Objective: To study the effect of mosquito age on the pyrethroid resistance and P450 monooxygenase activity in Anopheles sinensis in Huainan City, Anhui Province, China, as well as the molecular mechanism of pyrethroid resistance.

Methods: Anopheles mosquito larvae were collected in fields, and were emerged to adults. Then the pyrethroid resistance and P450 monooxygenase activity of female mosquitoes were detected 1, 3, 6, 9, 12, 15 d and 20 d after emergence.

Endemic characteristics of infantile visceral leishmaniasis in the People's Republic of China.

Background: Visceral leishmaniasis (VL) was once a severe parasitic disease in China. Thanks to the great efforts of integrated control, VL was eliminated in most epidemic areas, except for certain western provinces (autonomous region) at the end of 1950s. From then on, VL gained less attention and has seemed to spread, especially in the last 15 years.

[Study on malaria vectors in malaria endemic areas of Tibet autonomous region].

The malaria situation in Tibet has been in an active status and the malaria incidence reached the second in China in 2010. Malaria vector prevention and control is one of the important methods for malaria control, while the malaria vectors are still unknown in Tibet. The author summarized the past researches on malaria vectors in Tibet, so as to provide the evidence for improving malaria control investigation in malaria endemic areas of Tibet, with hopes to provide useful vector message for other researcher.

Malaria transmission potential in the Three Gorges Reservoir of the Yangtze River, China.

Objective: To define and evaluate the malaria transmission potential in the Yangtze River, following construction of the Three Gorges Reservoir.

Methods: Six villages, namely, Kaixian, Fengjie, Wanzhou, Fuling, Yubei, and Zigui were selected for investigating the malaria transmission potential in the reservoir. Transmission potential was estimated by mathematical modeling and evaluation of the local malaria situation.

[Study on the correlation between land use and cover change and malaria transmission in the areas along the Yellow River and Huai River].

Objectives: To study the major ecologic factors influencing the re-emergence of malaria in the areas along the Yellow River and Huai River by analyzing the relationship between the malaria incidence and the land use and cover change (LUCC).

Methods: The data of annual parasite incidence (API) and LUCC in the counties of Huaiyuan, Yongcheng and Tong ai in 1990-2006 were collected retrospectively. Considering the hysteresis effect of LUCC played on malaria transmission, analysis of LUCC in these counties were conducted based on the data of 1990-1995 and 1996-2000, while the API data in 1996-2000 and 2001-2005 were used to analyze the trends and changes of malaria incidence.