Association between antibiotic exposure and adverse outcomes of children and pregnant women: evidence from an umbrella review.

Background: Antibiotics are widely prescribed among children and pregnant women, but their safety profile is controversial. This study aimed to summarize and appraise current evidence for the potential impact of antibiotic exposure on pregnancy outcomes and children's health.

Methods: PubMed, Embase, Web of Science and the Cochrane Database of Systematic Reviews were searched from inception to June 2022.