A quality-comprehensive-evaluation-index-based model for evaluating traditional Chinese medicine quality.

Background: Evaluating traditional Chinese medicine (TCM) quality is a powerful method to ensure TCM safety. TCM quality evaluation methods primarily include characterization evaluations and separate physical, chemical, and biological evaluations; however, these approaches have limitations. Nevertheless, researchers have recently integrated evaluation methods, advancing the emergence of frontier research tools, such as TCM quality markers (Q-markers).

A general procedure for establishing composite quality evaluation indices based on key quality attributes of traditional Chinese medicine.

Licorice, a medicinal herb and food flavor ingredient, has been widely used in traditional Chinese medicine (TCM) for the past 4000 years. In this study, we propose a new quality evaluation approach for licorice quality control based on the key quality attributes commonly used in TCM. The high quality of TCM formulations is ensured by verifying the genuine origin and implementing good agricultural and collection practices for each medicinal herb.

Network Pharmacology-Based Strategy for Elucidating the Molecular Basis Forthe Pharmacologic Effects of Licorice ( spp.).

Licorice ( spp.) is used widely in traditional Chinese medicine (TCM) due to its numerous pharmacologic effects. However, the mechanisms of action of the chemical constituents of licorice and their structure-function relationships are not fully understood.

A Newly Discovered Phenylethanoid Glycoside from Bertoni Affects Insulin Secretion in Rat INS-1 Islet β Cells.

The tea-like beverage Bertoni () is popular in China because it reduces blood glucose and has a sweet taste. In this work, a comprehensive quality assessment of led to the discovery of five phenylethanoid glycosides, namely steviophethanoside (), cuchiloside (), salidroside (), icariside D (), and tyrosol (). Of them, compound is a novel compound.

Two new schisdilactone-type compounds from Schisandra chinensis.

Two new schisdilactone-type compounds, respectively, named schisdilactone H (1) and schisdilactone I (2), were isolated from the stems of Schisandra chinensis. The structures and absolute configurations of these new compounds were elucidated by extensive spectroscopic analysis as well as time-dependent density functional theory electronic circular dichroism calculations.

[HPLC determination of chemical constituents produced in Radix Polygoni Multiflori after processing].

Objective: To analysis the changes of two chemical constituents, namely 2, 3-dihydro-3, 5- dihydroxy-6-methyl-4H-pyran-4-one (DDMP) and 5-hydryoxymethyl-furfural (5-HMF) produced in Radix Polygoni Multiflori after processing, with processing time, and to determine the contents of 5-HMF in samples of Radix Polygoni Multiflori and Radix Polygoni Multiflori preparata.

Method: An HPLC method was applied with a Zobax SB-C18 (3.9 mm x 150 mm, 5 microm) column by a elution using methanol-water (10: 90) as the mobile phase.

[New chemical constituents from Radix Polygoni Multiflori after processing].

Objective: To study the new chemical constituents from Radix Polygoni Multiflori after processing.

Methods: Various kinds of chromatographic methods were used to deparate the chemical constituents from Radix Polygoni Multiflori after processing. Their structures were determined by NMR and MS spectral data.

[Determination of three chemical components in Fructus aurantii immaturus].

Objective: To determine the contents of 3 kinds of components in Fructus aurantii immaturus.

Method: HPLC analysis was performed to detect the contents of hesperidin, naringin and synephrine. The content of volatile oil was detected determined following the method of Chinese pharmacopoeia.