Publications by authors named "Lin Yuing Tan"
Background: This study aimed to translate and culturally adapt the Assessment of Quality of Life (AQoL)-6D into Malay (Malay-AQoL-6D), and assesses the instrument's acceptability, reliability, and validity among Malaysians living with chronic heart failure (HF).
Methods: The translation and cross-cultural adaptation process adhered to international guidelines. The Malay-AQoL-6D underwent content and face validity assessments via expert review, and pretesting among healthy individuals and patients with chronic conditions.
Article Synopsis
- - A new method for quickly synthesizing a specific type of chemical compound (7-amino-1,2,4-triazolo[1,5-a][1,3,5]triazine-2-propanamides) using microwave-assisted reactions has been developed, achieving results in just 5-10 minutes without the need for catalysts or complex purification methods.
- - Advanced techniques such as dynamic NMR spectroscopy and X-ray crystallography confirmed the structural characteristics of the synthesized compounds, revealing a unique 'C' shape and highlighting important molecular interactions like hydrogen bonding and π-stacking that affect their stability.
- - A variety of synthesized compounds were tested for their potential agricultural applications, showcasing promising herbicidal properties against a specific
Purpose: Health-related quality-of-life (HRQoL) data for the chronic heart failure (HF) population in Malaysia are lacking. Using EQ-5D-5L, this study intended to describe their HRQoL, identify predictors of worse HRQoL, and derive EQ-5D-5L index scores for use in economic evaluations.
Methods: A cross-sectional survey was conducted between April and September 2023 to collect EQ-5D-5L, sociodemographic, and clinical data from outpatients with HF across seven public specialist hospitals in Malaysia.
Two complementary pathways for the preparation of -substituted 3-(5-amino-1-1,2,4-triazol-3-yl)propanamides (5) were proposed and successfully realized in the synthesis of 20 representative examples. These methods use the same types of starting materials . succinic anhydride, aminoguanidine hydrochloride, and a variety of amines.
View Article and Find Full Text PDFA highly selective, one-pot, three-component synthesis of novel 2-alkyl-substituted 4-aminoimidazo[1,2-][1,3,5]triazines has been developed. The scope of the method was explored in two dimensions, varying the structures of trialkyl orthoesters and 2-aminoimidazoles in their reactions with cyanamide. Conveniently performed under microwave irradiation, this method was also proved to be efficient under conventional heating.
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