Publications by authors named "Lin Ying Shi"

Article Synopsis
  • Human exposure to perfluorooctanoic acid (PFOA) can lead to ulcerative colitis, but the mechanisms of its toxicity in intestinal cells remain unclear.
  • Researchers studied the effects of PFOA on human colorectal cancer cells (HCT116) by examining cell viability, mitochondrial activity, and gene expression related to metabolism.
  • They found that 300 μmol/L of PFOA significantly reduced the viability of HCT116 cells and altered metabolic gene expression, while lower concentrations (50 μmol/L) increased mitochondrial respiratory activity.
  • The study suggests that mitochondrial activity could indicate PFOA's effects, and specific genes could play a role in the development of ulcerative colitis linked to PFOA exposure
View Article and Find Full Text PDF
Article Synopsis
  • This study aimed to explore how platelet-rich plasma (PRP) influences macrophages to adopt the M2 type by regulating the AMPK signaling pathway.
  • Researchers used flow cytometry and Western blot to assess changes in macrophage markers and protein expressions after treating samples with various combinations, including LPS and PRP.
  • Findings showed that PRP enhances M2 marker CD206 and reduces M1 marker CD11c expression, while also activating the AMPK pathway; inhibiting AMPK diminished PRP's beneficial effects on macrophage polarization and TGF-β expression.
View Article and Find Full Text PDF

The Eu ion, with the 4f5d electronic configuration, is one of the most important activated ions due to its symmetry-allowed 4f → 5d electron transition. Herein, we successfully prepared a new type of blue phosphor, NaCsMg(PO):Eu (NCMP:Eu), in which Eu occupies the Na sites of the host lattice. Under 395 nm light excitation, a broad emission band from 410 to 550 nm can be seen, peaking at 458 nm, due to the 5d → 4f transition of Eu.

View Article and Find Full Text PDF

A new caesium sodium samarium borate phosphate, CsNaSm(BO)(PO), has been obtained successfully by the high-temperature solution growth (HTSG) method and single-crystal X-ray diffraction analysis reveals that it crystallizes in the orthorhombic space group Cmcm. The structure contains BO, PO, NaO and SmO polyhedra which are interconnected via corner- or edge-sharing O atoms to form a three-dimensional [NaSm(BO)(PO)] network. This network delimits large cavities where large Cs cations reside to form the total structure.

View Article and Find Full Text PDF

A new stibium phosphate, lithium barium bis(antimony oxide) tris(phosphate), LiBa(SbO)(PO), was prepared by the molten salt method with LiF as the flux. The crystal structure consists of an original three-dimensional anionic framework of [(SbO)(PO)] built from PO tetrahedra sharing their corners with SbO octahedra. This framework delimits one-dimensional tunnels where the lithium(I) and barium(II) ions are located.

View Article and Find Full Text PDF

Multiple myeloma (MM) is a common hematological malignancy and remains incurable. MiRNA-335 is a classic tumor suppressor, yet its expression pattern and biological role in MM is unclear. The aim of the present study was to determine the expression pattern, biological role, and mechanism of miR-335 in MM.

View Article and Find Full Text PDF

The enzymatic degradation behavior of hydroxyethyl cellulose (HEC) samples with different molar substitutions (MS) values was investigated. The changes in the molecular structure of HEC treated with enzymatic approach in comparison to the native HEC were studied through nuclear magnetic resonance (NMR), fourier transform infrared spectra (FTIR), X-ray diffraction (XRD) and scanning electron microscopy (SEM) techniques and kinetics of degradation was studied by viscometry. The cleavage of HEC chains could be observed from FTIR and kinetics results.

View Article and Find Full Text PDF

Background: The results of studies investigating the effect of green tea on glucose control and insulin sensitivity in humans are inconsistent.

Objective: We aimed to quantitatively evaluate the effect of green tea on glucose control and insulin sensitivity.

Design: We performed a strategic literature search of PubMed, EMBASE, and the Cochrane Library (updated to January 2013) for randomized controlled trials that evaluated the effects of green tea and green tea extract on glucose control and insulin sensitivity.

View Article and Find Full Text PDF

Objective: To study the differential microRNAs expression between patients with essential hypertension and healthy controls.

Methods: Whole blood from 15 hypertensive patients and 5 controls healthies were separated into plasma at 3000 rpm for 10 minutes. MicroRNAs were harvested using kit, and stored at -80°C.

View Article and Find Full Text PDF