Experience performing partial fistulectomy through a single incision to treat pyriform sinus fistula in children.

Background And Objectives: The surgical treatment of pyriform sinus fistula (PSF) is improving. The aim of this study was to investigate the effect of partial fistula excision in children with PSF assisted by using methylene blue.

Methods: According to the method used to treat PSF infection, the patients were divided into a conservative treatment group, a single incision group (the children drained the abscess through the incision at the dermatoglyph of the cricothyroid joint), and a non single incision group (the children drained the abscess through the incision in the most obvious area of the abscess or ulceration).

[Intervention with thumbtack needling on spinal low back pain in Air Force crew: a randomized controlled trial].

Objective: To observe the clinical effect on spinal low back pain (SLBP) in Air Force crew treated with novel thumbtack needling therapy and to analyze the relevant factors of the therapeutic effect.

Methods: A total of 120 Air Force crew with SLBP were randomized into a thumbtack needling group (40 cases), an external treatment group (40 cases, 1 case dropped off ) and a combined treatment group (40 cases, 1 case dropped off ). In the thumbtack needling group, the thumbtack needling therapy was adopted.

Totally implantable venous access ports: A prospective randomized study comparing subclavian and internal jugular vein punctures in children.

Background And Objectives: Totally implantable venous access ports (TIVAPs) are essential in children who require long-term intermittent intravenous therapy.

Methods: Patients who needed to undergo TIVAP implantation were randomly assigned to the internal jugular vein group or the subclavian vein group. The medical histories, operative details and major complications from the time of port implantation to 48 h after port removal were collected.

[Effect of NaHS on ATP-induced P2X receptor expression in rat microglia].

Objective: To observed the effect of sodium hydrosulphide (NaHS), a donor of HS on the cell viability,the membrane permeability and the expression of P2X receptor induced by adenosine triphosphate(ATP) in rat microglia.

Methods: Rat microglia in logarithmic growth phase was randomly divided into 4 groups. In control group, the cells were cultured without ATP treatment.

microRNA-221 Enhances MYCN via Targeting Nemo-like Kinase and Functions as an Oncogene Related to Poor Prognosis in Neuroblastoma.

is one of the most well-characterized genetic markers of neuroblastoma. However, the mechanisms as to how mediate neuroblastoma tumorigenesis are not fully clear. Increasing evidence has confirmed that the dysregulation of miRNAs is involved in MYCN-mediated neuroblastoma tumorigenesis, supporting their potential as therapeutic targets for neuroblastoma.

Clinical and experimental study of Castleman disease in children.

Background: Castleman disease (CD) is a rare lymphoproliferative disease that is often underdiagnosed or misdiagnosed, especially in children. For this reason, we describe the clinical manifestations, diagnosis and treatment of CD in 11 children.

Procedure: A retrospective study was performed to analyze the clinical features of 11 children with CD in a single institution from January 2001 to December 2012.