Publications by authors named "Lin Sheng Yang"

Article Synopsis
  • - The study aimed to assess the links between seven metal(loid)s (lead, manganese, nickel, arsenic, cadmium, chromium, vanadium) and hypertension in older Chinese adults, involving 1009 participants whose blood metal(loid) levels were measured.
  • - Findings showed a significant association between lead (Pb) and hypertension, with logistic regression revealing an odds ratio indicating higher hypertension risk among those with elevated Pb levels; this association remained when considering multiple metal(loid)s together.
  • - The research highlighted that the relationship between the metal(loid) mixture and hypertension could be influenced by factors like diabetes, age, BMI, and area, with Pb being the most significant metal affecting hypertension in older adults.
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Evidence on the impacts of PM1, PM2.5, and PM10 on the hospital admissions, length of hospital stays (LOS), and hospital expenses among patients with cardiovascular disease (CVD) is still limited in China, especially in rural areas. This study was performed in eight counties of Fuyang from 1 January 2015 to 30 June 2017.

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  • The study investigates the short-term effects of heat waves on cardiovascular health using data from over 62,000 participants between 2019-2021.
  • Researchers assessed 11 cardiovascular risk indicators, focusing on changes that occur during and after heat waves defined as persistently high temperatures.
  • Results show significant variances in cardiovascular indicators, with peak effects typically observed within 3 days; older adults, those with abnormal BMI, and diabetes patients were found to be particularly susceptible.
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The evidence about the effect of non-essential metal mixture on fasting plasma glucose (FPG) levels among older adults without diabetes is limited. This study aims to estimate the individual and joint relationship between five non-essential metals and FPG levels in Chinese older adults without diabetes. This study included 2362 older adults without diabetes.

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Background: Epidemiological studies about the effect of essential metal mixture on fasting plasma glucose (FPG) levels among elderly people are sparse. The object of this study was to examine the associations of single essential metals and essential metal mixture with FPG levels in Chinese community-dwelling elderly people.

Methods: The study recruited 2348 community-dwelling elderly people in total.

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Background: Previous studies have linked exposure to cold spells with cardiovascular diseases, however, underlying mechanisms remained to be understood. We aimed to explore the short-term effects of cold spells on hematocrit, a blood indicator associated with cardiovascular disease.

Methods: Our study was performed among 50,538 participants (68,361 health examination records) who visited the health examination centers of Zhongda Hospital in Nanjing City, China, during the cold seasons from 2019 to 2021.

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Most of studies relating ambient nitrogen dioxide (NO) exposure to hospital admissions for cardiovascular diseases (CVDs) were conducted among urban population. Whether and to what extent these results could be generalizable to rural population remains unknown. We addressed this question using data from the New Rural Cooperative Medical Scheme (NRCMS) in Fuyang, Anhui, China.

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The effects of interactions between the toxic and essential metal mixtures on cognitive function are poorly understood. This study aims to identify the joint association of arsenic (As), cadmium (Cd), and lead (Pb) with cognitive function in older adults and the moderating role of selenium (Se), zinc (Zn), and copper (Cu) in this association. This study included 1000 community-dwelling older adults.

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Located in central Asia, Xinjiang is characterized as a diverse environment in China, consisting of vast deserts, dotted oases, and high mountains. Due to the combined effect of climate conditions under such a diverse environment, there are large differences in human activities, living styles, and eating habits in farmland and grazing pastures between Xinjiang and other regions of China. This study aimed to investigate the variations and mechanisms of elemental distribution in the hair of Uyghur communities among different ages and genders and under different land use backgrounds in an oasis region in Xinjiang.

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Article Synopsis
  • - The study investigates the relationship between essential trace elements (ETEs) and atherosclerotic cardiovascular disease (ASCVD) risks in older Chinese adults, focusing on individual ETEs and their mixture over a span of 10 years.
  • - A total of 607 participants had their blood levels of specific ETEs (like chromium and selenium) measured to determine their impact on ASCVD risks, using established predictive equations and statistical models.
  • - Results indicated that higher blood levels of chromium and selenium correlate with lower ASCVD risks, along with positive associations with healthy cholesterol levels and negative associations with blood pressure.
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Background: The evidence about the effect of essential trace element (ETE) mixture on cognitive function amongst older adults is limited. This study aims to evaluate the associations of single ETEs and ETE mixture with cognitive function using a representative sample of community-dwelling older adults in China.

Methods: A total of 3814 older adults were included in the study.

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Background: Previous studies have found associations between single toxic metals, such as arsenic and cadmium, and kidney function in adults with diabetes. However, studies with regards to other metals and metal mixtures are still limited.

Objective: Our study aimed to investigate the associations between urinary concentrations of 5 selected metals and metal mixtures and kidney function using a sample of older adults with diabetes mellitus in Chinese communities.

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This study aimed to comprehensively analyze the effect of empty-nest on mental health and behaviors of the older population and explore the urban-rural differences. Data from the Cohort of Older People Health and Environment Controllable Factors were used, including 1071 older people aged 60 or over from a rural and an urban. Mental health, daily life behaviors, chronic physical diseases, and activities of daily living were evaluated.

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Background: Biomonitoring studies have demonstrated extensive exposure of infants, children, and pregnant women to phthalates, but data on phthalate exposure and their determinants in Chinese older adults remain insufficient. This study aims to assess urinary phthalate metabolite levels, individual and cumulative exposure risk, and their determinants in Chinese community-dwelling older adults.

Methods: A total of 987 individuals aged 60 years or over were included in this study.

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Article Synopsis
  • - The study investigated how marital status impacts cognitive function in older Chinese adults, involving 1,376 participants aged 60 and over, using the MMSE to measure cognitive ability.
  • - Results indicated that being single was linked to lower cognitive scores, especially significant among men, while the impact on women was not notable after adjusting for other factors.
  • - The findings suggest a need for targeted interventions for single older men to help mitigate cognitive decline as China's population continues to age.
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Pollution resulting from toxic trace elements is an increasing concern around the world especially in developing countries such as China. Rapid industrialisation, urbanisation and agricultural development are the dominant sources of anthropogenic contamination contributed to an increased potential toxicity of trace elements in the irrigation water-soil-food chain. Xin Jiang in China is a reserved cultivated land development area that could provide the most extensive strategic support for food production and arable land security in China.

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Attention-deficit/Hyperactivity disorder(ADHD) is a common neurodevelopmental disorder among children. Traditional assessment methods generally rely on behavioral rating scales (BRS) performed by clinicians, and sometimes parents or teachers. However, BRS assessment is time consuming, and the subjective ratings may lead to bias for the evaluation.

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  • The study investigates the relationship between phthalate exposure and obesity among elderly individuals in China, focusing on a sample from Lu'an, Anhui province.
  • Researchers analyzed urine samples for seven phthalate metabolites and used health metrics like body mass index and waist circumference to assess obesity.
  • Findings revealed that over half the participants were generally obese, and significant associations were found between several phthalate metabolites and both general and abdominal obesity, with variations noted between genders.
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Natural iron-containing minerals present in the geosphere in the form of crystalline minerals can be used as adsorption material for removal of arsenic from wastewater and remediation of arsenic-contaminated soils. In this paper, the adsorption and desorption of arsenic onto different iron-containing materials including hematite, limonite, siderite, ilmenite, magnetite, FeO, FeO, and Fe-Mn binary oxide (FMBO) were studied in laboratory experiments. The mechanism of arsenic adsorption was analyzed by scanning electron microscopy (SEM), X-ray diffraction (XRD), and fourier transform infrared spectroscopy (FTIR).

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Objective: To investigate the molecular mechanisms of the adverse effects of exposure to sulfamonomethoxin (SMM) in pregnancy on the neurobehavioral development of male offspring.

Methods: Pregnant mice were randomly divided into four groups: control- (normal saline), low- [10 mg/(kg•day)], middle- [50 mg/(kg•day)], and high-dose [200 mg/(kg•day)] groups, which received SMM by gavage daily during gestational days 1-18. We measured the levels of short-chain fatty acids (SCFAs) in feces from dams and male pups.

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The concentration level related to toxicities of trace elements in drinking water, rice, wheat flour, and their associated negative impacts on human health have become an emergent issue in China. Because Xinjiang is the largest province in China with the majority of arable pasture land available for cultivation, it is important to analyze the concentrations of trace elements in relation to their toxicities in water, rice, and wheat flour and to investigate the health risk differences between agricultural and pastoral areas in Bay County, Xinjiang. The study results showed that (1) metal concentrations from drinking water, rice, and wheat flour were within the permissible limits; (2) concentration levels of trace elements and their total risk from drinking water and rice were higher in the agricultural areas than those in the pastoral areas, whereas concentration levels of trace elements and their total risk from wheat flour were higher in the pastoral areas than those in the agricultural areas; (3) the concentration level of the trace elements in rice were higher than in the wheat flour, but the risk from the wheat flour was higher than the risk from rice; (4) total non-cancer risk from the flour (HI) in both areas exceeded the respective safe reference doses; (5) total cancer risk from the wheat flour, rice, and water exceeded the safety limit (1 × 10); (6) for the exposed population, arsenic was suggested as the most evident pollutant leading to carcinogenic concerns regarding the water, rice, and wheat flour; (7) the risk index from the wheat flour made up the highest percentage both in the total cancer risk and the non-cancer risk, followed by rice and then water; and (8) the human health risk was attributed to influence from the local environment in the agriculture areas, while it was attributed to the external environment in the pastoral areas.

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Background: A vegetarian diet may be a risk factor for depression, but this relationship was unclear in the elderly Chinese population.

Methods: Self-report data were gathered from 1051 elderly persons using the Cohort of Elderly Health and Environment Controllable Factors, which was created in West Anhui, China. The depressive symptoms were set as binary, ordinal, and continuous outcomes, respectively, whereas the dietary structures were computed as an ordinal variable and a dummy variable.

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Objective: The effects of arsenic exposure from drinking water, arsenic metabolism, and arsenic methylation on blood pressure (BP) were observed in this study.

Methods: The BP and arsenic species of 560 participants were determined. Logistic regression analysis was applied to estimate the odds ratios of BP associated with arsenic metabolites and arsenic methylation capability.

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Background: Little is known about the association between weight changes and adverse health outcomes among Chinese adults.

Methods: A total of 1715 Chinese adults, 45-60 years of age, have been recruited to participate in the Hefei Nutrition and Health Study started in 2012. Multivariate logistic regression analysis was performed to determine the association of weight changes since age 20 (loss ≥5.

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In order to investigate the effect of long-term (1991—2013) K fertilizer deficiency and surplus on potassium-bearing mineral and K nutrition of purple soil-soil primary, clay mineral composition and potassium (K) nutrition were determined on the long-term experiment of fertility and fertilizer efficiency in neutral purple soil by using X-ray diffraction (XRD) analysis technique. Five soil samples were selected from soil samples library for soil mineral analysis, including original soil, which preserved in 1991 before the experiment carrying out; K deficient treatment for 12 years and 22 years, which means no K fertilizer was applied during 1991—2003 and 1991—2013, respectively; and K surplus treatment for 12 years and 22 years, which means excess K fertilizer was applied during 1991—2003 and 1991—2013, separately. The result showed that, soil potassium-bearing primary mineral, such as mica, potassium feldspar, had apparently weathered and slaked for the K deficient treatment and the weathered extent gradually aggravated following fertilization ages, demonstrating fertilization for 22 years<12years View Article and Find Full Text PDF