Publications by authors named "Lin Meng"

Although the significance of some plant WRKYs in response to cold stress have been identified, the molecular mechanisms of most WRKYs remain unclear in grapevine. In this study, we demonstrate that cold-induced expression of in executes a beneficial role in enhancing resistance by the regulating starch decomposition. VaWRKY65 was identified as an upstream transcriptional activator of through yeast one-hybrid library screening and validated to directly interact with the W-box region inside the promoter.

View Article and Find Full Text PDF

Background: IVIM is a useful quantitative tool for predicting prognosis, but it is labor-intensive. Simplified b-value settings and post-processing could be more practicable for clinical applications.

Purpose: To assess the value of model-free parameters (virtual MR elastography [vMRE] and signature-index [S-index]) derived from IVIM in evaluating pathological indicators and long-term survival in nasopharyngeal carcinoma (NPC), and to compare those with model-based parameters.

View Article and Find Full Text PDF

Background: To explore a novel semi-automatic quantitative method for detecting lid-wiper epitheliopathy (LWE) and analyze its impact on the distribution of corneal epithelial thickness (CET).

Methods: A total of 37 eyes from 37 adults were included in this study. The lid wipers were stained with lissamine green strips, and the stained areas were recorded using a digital slit-lamp biomicroscopy and analyzed using ImageJ software.

View Article and Find Full Text PDF

Objective: Intracerebral haemorrhage significantly impacts patients' functional and motor recovery. Identifying predictive factors is crucial for enhancing post-intracerebral haemorrhage rehabilitation strategies. This study explores the predictors of functional improvement and motor recovery in intracerebral haemorrhage survivors.

View Article and Find Full Text PDF

The brain-computer interface (BCI) based on rapid serial visual presentation (RSVP) provides a novel approach for efficiently optimizing traditional machine-based target detection, revealing a broad application prospect in security, entrainment, monitoring, etc. A bottleneck of current RSVP-BCI is that its detectable result is limited to a binary way, i.e.

View Article and Find Full Text PDF

The ability to efficiently detect error is fundamental for human adaptive behaviors, and plays an increasingly crucial role in developing more intelligent brain-computer interface (BCI). Error-related potential (ErrP), which can reflect prediction error, has been widely used by the BCI to read whether outcomes accord with users' expectation or not. However, current ErrP-BCI cannot distinguish the prediction error is induced by user's own (first-person perspective, 1PP) or other's (third-person perspective, 3PP) wrong action, hindering it from being applied in social interactions.

View Article and Find Full Text PDF

Parkinson's disease (PD) patients exhibit more impaired gait performance during motor cognitive dual-task tests. However, the effects of motor and cognitive task complexity on early PD identification have not been systematically investigated. 25 idiopathic early PD patients and 14 age-matched healthy elders were recruited and required to perform a complex motor task with/ without three different cognitive tasks.

View Article and Find Full Text PDF

The assessment of motor fluctuation is essential for patients with Parkinson's Disease (PD). However, the clinical scales are unable to sufficiently reflect motor fluctuations due to their lower sensitivity to subtle changes. Therefore, in this study, we proposed an inertial-based gait normalcy index (GNI) derived from deviations of gait spatiotemporal parameters related to a healthy age-matched baseline.

View Article and Find Full Text PDF

Polygenic risk scores (PRS) hold prognostic value for identifying individuals at higher risk of type 2 diabetes (T2D). However, further characterization is needed to understand the generalizability of T2D PRS in diverse populations across various contexts. We characterized a multi-ancestry T2D PRS among 244,637 cases and 637,891 controls across eight populations from the Population Architecture Genomics and Epidemiology (PAGE) Study and 13 additional biobanks and cohorts.

View Article and Find Full Text PDF

As one of the main motor indicators of Parkinson's disease (PD), postural instability and gait disorder (PIGD) might manifest in various but subtle symptoms at early stage resulting in relatively high misdiagnosis rate. Quantitative gait assessment under dual task or complex motor task (i.e.

View Article and Find Full Text PDF

Expanding the application possibilities of brain-computer interfaces (BCIs) is possible through their implementation in mixed reality (MR) environments. However, visual stimuli are displayed against a realistic scene in the MR environment, which degrades BCI performance. The purpose of this study was to optimize stimulus colors in order to improve the MR-BCI system's performance.

View Article and Find Full Text PDF

Previous studies have validated that different balance tasks induce different cortical responses, which are key indexes of balance assessment. Assessing balance is crucial for stroke survivors to prevent falls and improve rehabilitation outcomes. However, it was unclear whether these tasks may affect the balance assessment, particularly regarding the relationship between task difficulty and the corresponding cortical responses involved in balance control.

View Article and Find Full Text PDF

A new stripe rust resistance gene YrAn1589 in Chinese wheat Annong1589 was mapped to a 160.9-166.6 kb interval on chromosome arm 3BL and co-segregated with a marker CAPS9 developed from candidate gene TraesCS3B03G1054600.

View Article and Find Full Text PDF

Precision treatment of gastric cancer requires specific biomarkers, and CLDN18.2 emerges as a promising target for patients' stratification and therapeutic guidance. In 563 cases, 54.

View Article and Find Full Text PDF

Purpose: To evaluate the value of model-free parameters (virtual magnetic resonance elastography [vMRE] and signature index [S-index]) and tumor aggressiveness indicators (contralateral pharyngeal recess invasion [CPRI] and tumor growth type [TGT]) in forecasting 5-year treatment outcomes in nasopharyngeal carcinoma (NPC).

Materials And Methods: A total of 106 patients were included in this study. Only two b-values were employed to calculate vMRE and S-index.

View Article and Find Full Text PDF

Background: Dual fluoroscopic imaging system (DFIS) was employed to identify the Center of Rotation(COR) in the lower lumbar spine and determine its relationship with weight bearing.

Methods: In this study, twenty participants were recruited. A 3D model of each participant's lumbar spine was created using CT images, and their relative positions were determined through DFIS.

View Article and Find Full Text PDF

The accurate estimation of regional crop yields holds significant importance for optimizing subsequent resource allocation and maximizing economic returns in agriculture. Crop yield can be effectively estimated by assessing the overall growth status through long-term remote sensing observations. However, most previous studies have relied on remote sensing data from one or a few periods for yield estimation, thus lacking a comprehensive description of entire crop growth.

View Article and Find Full Text PDF

Regulatory T (Treg) cells are known to impede antitumor immunity, yet the regulatory mechanisms and functional roles of these cells remain poorly understood. In this study, through the characterization of multiple cancer models, we identified a substantial presence of peripherally induced Treg cells in the tumor microenvironment (TME). Depletion of these cells triggered antitumor responses and provided potent therapeutic effects by increasing functional CD8+ T cells.

View Article and Find Full Text PDF

Designing voxelized composite structures via 4D printing involves creating voxel units with distinct material properties that transform in response to stimuli; however, optimally distributing these properties to achieve specific target shapes remains a significant challenge. This study introduces an optimization method combining deep learning (DL) and an evolutionary algorithm, focusing on a solvent-responsive hydrogel as the target material. A sequence-enhanced parallel convolutional neural network is developed and generated a dataset through finite element simulations.

View Article and Find Full Text PDF

Hydrogen peroxide (HO) finds wide application in disinfection, chemical production, and bleaching owing to its sustainability and ease of storage compared to hydrogen. However, the current industrial engineering practices for producing photocatalysts used in HO generation face challenges such as low yields with organic catalysts and high costs associated with inorganic catalysts. In light of these challenges, we investigate a viable method utilizing a simple condensation reflux technique to synthesize pure organic heterojunction photocatalysts featuring a π-π stacked structure derived from graphitized carbon nitride (melem) and meso-tetrakis (4-carboxyphenyl) porphyrin, enabling efficient HO production without the necessity of sacrificial agents.

View Article and Find Full Text PDF

It is well-known that cancer-associated fibroblasts (CAFs) are involved in the desmoplastic responses in Head and Neck Squamous Cell Carcinoma (HNSCC). CAFs are pivotal in the tumor microenvironment (TME) molding, and exert a profound influence on tumor development. The origin and roles of CAFs, however, are still unclear in the HNSCC, especially antigen-presenting cancer-associated fibroblasts (apCAFs).

View Article and Find Full Text PDF

Scoliosis is a prevalent condition among adolescents, and the spinal manipulation is one of the conservative treatment methods for scoliosis patients. Impairment in movement function stands out as a typical characteristic in cases of scoliosis. This study utilized a single-arm clinical trial design involving 35 patients aged 18 to 20 with idiopathic scoliosis (IS) and Cobb angles ranging from 10° to 30°.

View Article and Find Full Text PDF

Background And Purpose: To investigate the value of arterial spin labeling (ASL) and radiological depth of invasion (rDOI) in predicting long-term treatment outcomes in nonmetastatic nasopharyngeal carcinoma (NPC).

Materials And Methods: A total of 113 patients with NPC were included and randomly divided into training (n = 81) and validation (n = 32) cohorts. Tumor blood flow (TBF) parameters derived from the ASL (TBF, TBF, and nTBF) were obtained.

View Article and Find Full Text PDF

Neoadjuvant chemoradiotherapy (nCRT) is the standard treatment for locally advanced rectal cancer (LARC). Pathological complete regression is closely linked to disease outcomes. However, biomarkers predicting nCRT response and patient survival are lacking for LARC.

View Article and Find Full Text PDF

Genetic summary data are broadly accessible and highly useful, including for risk prediction, causal inference, fine mapping, and incorporation of external controls. However, collapsing individual-level data into summary data, such as allele frequencies, masks intra- and inter-sample heterogeneity, leading to confounding, reduced power, and bias. Ultimately, unaccounted-for substructure limits summary data usability, especially for understudied or admixed populations.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionmb9hth4nq4hscqr6g7sflbad6tes0pa7): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once