Publications by authors named "Limor Toledano"
Recent guidelines recommended removing metronidazole as a therapeutic option for infections (CDI). However, superiority of vancomycin over metronidazole in mild CDI is not established and use of vancomycin might lead to emergence of vancomycin-resistant enterococci (VRE). A retrospective cohort study and efficacy analyses were conducted at Shamir Medical Center, Israel (2010-2015), among adults with acute CDI.
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- The study investigates the effectiveness of vancomycin versus metronidazole for treating mild Clostridium difficile infections (CDI), as current data on this is limited.
- It was conducted on 260 adult patients and found no significant differences in clinical outcomes between the two treatments for those with mild CDI.
- The findings suggest that metronidazole is preferable for mild CDI, and using vancomycin is linked to a higher risk of later infection with vancomycin-resistant Enterococcus (VRE).