Publications by authors named "Limor Parker"

Background: Familial Steroid-sensitive Nephrotic Syndrome (SSNS) is rare, complicating the identification of candidate genes. A recent population-based approach study of SSNS identified HLA-DQA1 and Phospholipase C-Gamma 2 (PLCG2) missense coding variants as candidate loci. PLCG2 is a signaling molecule regulated by phosphorylation and is critical for Ca flux in cells of the immune system.

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Article Synopsis
  • Acute hemorrhagic edema of infancy (AHEI) is a rare, self-limiting vasculitis affecting small blood vessels in infants, often following a viral infection.
  • A study reviewed 26 hospitalized children over 10 years, revealing typical symptoms of rash and swelling, particularly in the legs, with some patients experiencing systemic complications.
  • The findings indicate a higher than previously reported rate of complications, emphasizing the importance for pediatricians to recognize and manage AHEI effectively.
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