Water temperature exhibits an overwhelming effect on the spatial allocation of sediment phosphorus fractions in the permanent backwater area of the Three Gorges Reservoir, China.

The upstream cascade reservoirs and the implementation of soil and water conservation practices have effectively mitigated sediment inflow to the Three Gorges Reservoir (TGR) since it was fully operational in 2010. However, total deposited sediments and algal blooms in its tributaries have increased during the post-TGR period. To investigate the spatial distribution characteristics of deposited fractional phosphorus in sediments and its influencing factors, column sediment and overlying water datasets collected from field campaigns were analysed using the multivariate statistical approaches by Partial Triadic Analysis (PTA) and Redundancy Analysis (RDA).

Eukaryotic plankton community and assembly processes in a large-scale water diversion project in China.

The Middle Route of the South to North Water Diversion Project (MRP) and its water source, the Danjiangkou Reservoir (DJK), play a pivotal role in mitigating the chronic water scarcity challenges faced by northern China. Eukaryotic plankton are widespread in aquatic ecosystems, which are crucial for the water quality stability of DJK and MRP, yet comparative studies on their contemporaneous dynamics and assembly processes are scarce. In this study, amplicon sequencing was used to investigate the eukaryotic plankton communities.

Selection of the Anti-Osteoporosis Active Ingredients of Fructus Psoraleae-Eucommia-Drynariae Rhizoma Based on Solid-Phase Bio-Cell Chromatography and HPLC-MS Analysis.

Osteoporosis (OP) is a prevalent metabolic bone disease globally. Currently, the development of Traditional Chinese Medicine (TCM) resources to unblock joints, strengthen bones, and enhance muscle function to regulate anti-osteogenic and anabolic metabolism and thus reshape intraosseous homeostasis was an effective way to alleviate OP. The F-E-D formula, comprising Fructus Psoraleae, Eucommia, and Drynariae Rhizoma, has shown efficacy in treating OP.

Weighted comprehensive risk assessment and pollution analysis of long-term printing and dyeing sludge landfills in an industrialized Chinese city.

Sludge landfilling is widely used in China, accounting for approximately 65% of total sludge disposal, due to its simplicity and cost-effectiveness. However, with increasing land scarcity and stricter environmental regulations, the Chinese government has emphasized reducing sludge landfilling. Despite these efforts, sludge historically disposed of in landfills continues to pose risks, including heavy metal leaching and contamination of groundwater and soil.

Self-Adhesive Elastic Conductive Ink with High Permeability and Low Diffusivity for Direct Printing of Universal Textile Electronics.

Elastic conductive ink (ECI) can effectively balance the electromechanical properties of printed flexible electronics. It remains challenging to realize ECIs for direct printing on deformable porous substrates with complex textures, such as textiles, to form continuous and stable electrical paths. We engineered a self-adhesive ECI with high permeability and low diffusivity, achieving efficient electrode printing on a wide range of textiles with material and structure diversity.

Genome-wide discovery of CBL genes in Bobr. and functional analysis of under drought and salt stress.

Calcineurin B-like (CBL) proteins are a class of important Ca receptors that play key roles in plant stress response. CBLs have been shown to participate in responses to abiotic stresses such as drought, salt, and cold in many plant species, including and rice. However, little is known about their potential functions in the desert halophyte .

Androgens have therapeutic potential in T2 asthma by mediating METTL3 in bronchial epithelial cells.

Studies have shown that androgens can alleviate the symptoms of T2 asthma and are inversely correlated with the severity of allergic asthma. METTL3, a crucial component of m6A modification, mitigates the development of T2 asthma by inhibiting Th2 cell differentiation. However, the impact of androgens, such as dihydrotestosterone (DHT), on the progression of T2 asthma through METTL3 has yet to be investigated.

Microfiber Actuators With Hot-Pressing-Programmable Mechano-Photothermal Responses for Electromagnetic Perception.

Electromagnetic radiation (EMR) is a ubiquitous harm and hard to detect dynamically in multiple scenarios. A mechano-photothermal cooperative microfiber film (MFF) actuator is developed that can synchronously detect EMR with high reliability. The programmable actuation is deployed by a hot-pressing methodology, achieving the MFF with moderate modulus (378 MPa) and superior toughness (87.

SUMO3 inhibition by butyric acid suppresses cell viability and glycolysis and promotes gemcitabine antitumor activity in pancreatic cancer.

Background: Excavation of key molecules can help identify therapeutic targets and improve the prognosis of pancreatic cancer. This study evaluated the roles of SUMO3 in cell viability, glycolysis, gemcitabine (GEM) sensitivity, and the antitumor activity of butyric acid (BA) in pancreatic cancer.

Methods: The mRNA and protein levels of SUMO3 were detected by qRT-PCR, Western blot, and immunohistochemical assay.

Bioenergy recovery and carbon emissions benefits of short-term bio-thermophilic pretreatment on low organic sewage sludge anaerobic digestion: A pilot-scale study.

Sewage sludge in cities of Yangzi River Belt, China, generally exhibits a lower organic content and higher silt contentdue to leakage of drainage system, which caused low bioenergy recovery and carbon emission benefits in conventional anaerobic digestion (CAD). Therefore, this paper is on a pilot scale, a bio-thermophilic pretreatment anaerobic digestion (BTPAD) for low organic sludge (volatile solids (VS) of 4%) was operated with a long-term continuous flow of 200 days. The VS degradation rate and CH yield of BTPAD increased by 19.

Inhibition of DNMT1 attenuates experimental food allergy.

Background: The treatment of food allergy (FA) needs improvement. The treatment of immune disorders can be improved by regulating epigenetic marks, which is a promising method. The objective of this research is to alleviate experimental FA by employing an inhibitor of DNA methyltransferase-1 (DNMT1).

Synergistic Bipolar Irreversible Electroporation for Tumor Ablation Without Muscle Contraction.

Irreversible electroporation (IRE) has emerged as a promising modality for tumor ablation, leveraging the controlled application of electrical pulses to induce cell death. However, the associated muscle contractions during the procedure pose challenges. This study introduces a novel approach, termed Synergistic Bipolar Irreversible Electroporation (SBIRE), aimed at achieving tumor ablation without the undesirable side effect of muscle contraction.

Experimental investigation and simulation analysis of cast-steel joints under vertical pressure.

The joint made of cast steel is frequently utilized within a treelike column structure to ensure a smooth transition. It is of great significance in ensuring the overall structural safety, but currently, the mechanical property and bearing capacity of this type of joint cannot be fully understood. This study investigates the load characteristics of three-forked cast steel joints through concrete experiments, finite element analysis, and regression method formula derivation, filling the gap in mechanical properties and calculation formulas of forked cast steel joints.

METTL3 mediates SOX5 m6A methylation in bronchial epithelial cells to attenuate Th2 cell differentiation in T2 asthma.

Objective: Asthma, a chronic inflammatory disease in which type 2 T helper cells (Th2) play a causative role in the development of T2 asthma. N6-methyladenosine (m6A) modification, an mRNA modification, and methyltransferase-like 3 (METTL3) is involved in the development of T2 asthma by inhibiting Th2 cell differentiation. Sex determining region Y-box protein 5 (SOX5) is involved in regulating T cell differentiation, but its role in T2 asthma was unclear.

Gender differences in gastrointestinal, biopsychosocial and healthcare-seeking behaviors in Chinese patients with irritable bowel syndrome predominant with diarrhea.

Background: Evidences of comparison of sex difference in Chinese irritable bowel syndrome (IBS) patients were few. We aim to compare gender difference in the biopsychosocial characteristics of Chinese patients of IBS predominant with diarrhea (IBS-D).

Methods: IBS-D patients meeting Rome III criteria were enrolled.

Genome-Wide Analysis of the Gene Family under Abiotic Stress and Characterization of the Gene.

Heat shock factors (Hsfs) play a crucial role in plant defense processes. However, the distribution and functional characteristics of Hsf genes in the relict plant are still unclear. In this study, a total of 19 were identified and divided into three separate subgroups, comprising 10 , 7 , and 2 genes, respectively, based on their phylogenetic tree and the presence/absence of conserved protein domains.

[Analysis of the efficacy of high tibial osteotomy combined with medial meniscus centralization in knee osteoarthritis].

Objective: To explore the efficacy of high tibial osteotomy （HTO） combined with medial meniscus centralization in knee osteoarthritis.

Methods: A total of 26 patients who underwent surgery from October 2018 to October 2020 were reviewed. Among them, 14 patients underwent high tibial osteotomy combined with arthroscopic meniscus centralization surgery were centralized group, including 8 males and 6 females, with an average age of （50.

Liquiritin reduces chondrocyte apoptosis through P53/PUMA signaling pathway to alleviate osteoarthritis.

Aims: The main pathological features of osteoarthritis (OA) include the degeneration of articular cartilage and a decrease in matrix synthesis. Chondrocytes, which contribute to matrix synthesis, play a crucial role in the development of OA. Liquiritin, an effective ingredient extracted from Glycyrrhiza uralensis Fisch.

The effect of music tempo on movement flow.

There has been much controversy over the effects of music tempo on movement flow. In this study, a single-factor repeated-measurement design was used to explore the effect of music tempo (fast, slow, and no music control) on movement flow by measuring both subjective experiences and objective electroencephalographic (EEG) characteristics during brisk walking. In the experiment, 20 college students walked briskly on a treadmill using EEG equipment.

Retrospective cohort study on the correlation analysis among peri-procedural factors, complications, and local tumor progression of lung tumors treated with CT-guided microwave ablation.

Background: Despite adherence to guidelines, recurrence of lesions remains possible in lung tumor microwave ablation (MWA) even when termination is enabled by 5-10 mm ground glass changes. Limited evidence exists regarding the correlation between timely management of perioperative complications (including pneumothorax, pleural effusion, hemorrhage, cavity formation, and infection) and local tumor progression. This retrospective study aimed to investigate the relationship among peri-procedural factors, complications, and local tumor progression in 164 cases of lung tumors treated with computed tomography-guided MWA (CT-MWA), and improve the local prognosis and reduce the complication rate of CT-guided lung tumor ablation.

Microstructure and hydrogen storage properties of the MgYNiCo (x = 0, 0.2, 0.3, and 0.4) alloys.

Rare earth elements have excellent catalytic effects on improving hydrogen storage properties of the MgNi-based alloys. This study used a small amount of Y to substitute Mg partially in MgNiCo and characterized and discussed the effects of Y on the solidification and de-/hydrogenation behaviors. The MgYNiCo (x = 0, 0.