A Novel Splice-Site Variation in Causes Keratoconus in an Indian Family.

Objective: This study aims to clarify the association between keratoconus (KC) and potential pathogenic genetic variants in a three-generation South Indian family.

Methods: In the present study, a three-generation KC family, which comprised 10 affected patients and nine unaffected individuals, was recruited. The family history and necessary ophthalmological exams, such as visual acuity and slit-lamp, were performed for all participants.

[Clinical analysis of real-time iris recognition guided LASIK with femtosecond laser flap creation for myopic astigmatism].

Objective: To assess the safety, efficacy, stability and changes in cylindrical degree and axis after real-time iris recognition guided LASIK with femtosecond laser flap creation for the correction of myopic astigmatism.

Methods: Retrospective case series. This observational case study comprised 136 patients (249 eyes) with myopic astigmatism in a 6-month trial.