Objective: To observe regulatory effect of Naoluoxintong formula (, NLXT) and its split prescriptions on vascular regeneration of rats suffering from cerebral ischemia-reperfusion (IR) syndrome of Qi deficiency with blood stasis (QDBS).
Methods: NLXT is the representative prescription of Yiqi Huoxue Tongluo decoction, and NLXT is divided into Yiqi herbs and Huoxue Tongluo herbs according to their efficacies. One hundred and eight specific-pathogen-free, clean-grade, Sprague-Dawley male rats were selected to prepare the classical rat model with QDBS due to middle artery ischemia-reperfusion using the multi-factor compound simulation approach.
We reveal and justify, both theoretically and experimentally, the existence of a unifying criterion of the boiling crisis. This criterion emerges from an instability in the near-wall interactions of bubbles, which can be described as a percolation process driven by three fundamental boiling parameters: nucleation site density, average bubble footprint radius and product of average bubble growth time and detachment frequency. Our analysis suggests that the boiling crisis occurs on a well-defined critical surface in the multidimensional space of these parameters.
View Article and Find Full Text PDFThe riparian zone supports important ecological functions and acts as an ecotone connecting terrestrial and aquatic areas. Soil microbes under the revegetation of woody species are crucial to the biogeochemical cycle of nutrients. Here, soil samples were collected to examine the soil microbes during different emergence phases in 2019 (May:T1, July:T2, and September:T3) in the riparian zone of the Three Gorges Reservoir, China.
View Article and Find Full Text PDFMedicine (Baltimore)
February 2023
Rationale: Anti-GQ1b antibody syndrome originates in the peripheral nervous system or the central nervous system. Various overlapping syndromes and atypical manifestations are also seen in clinic. It is rare to see multiple sites (almost all targets) of central and peripheral damage at the same time, resulting in brain death-like changes in patient.
View Article and Find Full Text PDFFor more than 20 years, disaster dynamic monitoring and early warning have achieved orderly and sustainable development in China, forming a systematic academic research system and top-down policy design, which are inseparable from the research of China's scientific community and the promotion of government departments. In the past, most of the research on dynamic disaster monitoring and early warning focused on specific research in a certain field, scene, and discipline, while a few studies focused on research review or policy analysis, and few studies combined macro and meso research reviews in academia with national policy analysis for comparative analysis. It is necessary and urgent to explore the interaction between scholars' research and policy deployment, which can bring theoretical contributions and policy references to the top-down design, implementation promotion, and academic research of China's dynamic disaster monitoring and early warning.
View Article and Find Full Text PDFBackground: Better outcome prediction could assist in reliable classification of the illnesses in neurological intensive care unit (ICU) severity to support clinical decision-making. We developed a multifactorial model including quantitative electroencephalography (QEEG) parameters for outcome prediction of patients in neurological ICU.
Methods: We retrospectively analyzed neurological ICU patients from November 2018 to November 2021.
Background: Naoluo Xintong decoction (NLXTD) is a traditional Chinese medicine (TCM) formula which has been used to improve neuronal functional recovery after cerebral ischemic stroke. However, the molecular mechanism underlying NLXTD's amelioration of ischemic stroke remains unclear. The present study was designed to explore the effect and mechanism of NLXTD on brain angiogenesis in a rat model with cerebral ischemia-reperfusion (I/R) injury targeting the hypoxia-inducible factor-1 (HIF-1)/vascular endothelial growth factor (VEGF) pathway.
View Article and Find Full Text PDFThe construction of dams has caused riparian habitat degradation and ecosystem service loss globally. It is critical to assess the response of riparian plant communities to inundation gradients for their conservation. Recent evidence suggests that plant community assemblages are governed by flooding stress, soil nutrient availability, climate (environmental filtering) and dispersal, speciation, local extinction (dispersal filtering), but it remains unclear which dominates the riparian ecosystem regulated by a dam.
View Article and Find Full Text PDFSubmergence impedes photosynthesis and respiration but facilitates aerenchyma formation in bermudagrass. Still, the regulatory genes underlying these physiological responses are unclear in the literature. To identify differentially expressed genes (DEGs) related to these physiological mechanisms, we studied the expression of DEGs in aboveground and underground tissues of bermudagrass after a 7 d treatment under control (CK), shallow submergence (SS), and deep submergence (DS).
View Article and Find Full Text PDFMany rivers across the globe are regulated by dams, resulting in a strong alteration of the plant community composition of the drawdown zone. But, how these changes happen along the drawdown zone is less understood. In this study, a multivariate analysis was used to explore plant composition and similarity along the drawdown zone of the Three Gorges Dam Reservoir (TGDR), China.
View Article and Find Full Text PDFWe present the first experimental observations of scale-free behavior in the bubble footprint distribution during the boiling crisis of water, in pool and flow boiling conditions. We formulate a continuum percolation model that elucidates how the scale-free behavior emerges from the near-wall stochastic interaction of bubbles and provides a criterion to predict the boiling crisis. It also offers useful insights on how to engineer surfaces that enhance the critical heat flux limit.
View Article and Find Full Text PDFThe concept of resilience can be realized in natural and engineering systems, representing the ability of a system to adapt and recover from various disturbances. Although resilience is a critical property needed for understanding and managing the risks and collapses of transportation systems, an accepted and useful definition of resilience for urban traffic as well as its statistical property under perturbations are still missing. Here, we define city traffic resilience based on the spatiotemporal clusters of congestion in real traffic and find that the resilience follows a scale-free distribution in 2D city road networks and 1D highways with different exponents but similar exponents on different days and in different cities.
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