[ study on the effects of intercellular adhesion operon of on the inflammation associated with bacteria-fungal mixed biofilm].

Objective: To study the effect of intercellular adhesion (ica) operon of on the inflammation associated with mixed biofilm of and on endotracheal tube material in rabbits.

Methods: The standard strains of RP62A (ica operon positive, positive group) and ATCC12228 (ica operon negative, negative group) were taken to prepare a bacterial solution with a concentration of 1×10 CFU/mL, respectively. Then, the two bacterial solutions were mixed with the standard strain of ATCC10231 of the same concentration to prepare a mixed culture solution at a ratio of 1∶1, respectively.