[Induction of the monooxygenase activity in fish tissues by polycyclic aromatic hydrocarbons and its use in the biomonitoring of water pollution].

Monooxygenase activity changes in the liver and in other tissues of certain fish species were studied after injection of methylcholanthrene and aminoanthracene to fish. Determinations of the benz(a)pyrene hydroxylase activity and activity of 7-ethoxycoumarine 0-dealkylation in the monooxygenase system were proposed as test-systems for the control of polycyclic hydrocarbon contents in natural and waste waters. The metabolic activation (Aim's test) performed by the liver microsomal fractions of different fish species was used for the analysis of sulfate cellulose industry waste waters.

[Comparative-biochemical study of phosphoinositides as functionally active components of excitable nerve fiber membranes].

The effect of acetylcholine (ACh) and cyclic 3',5'-adenosine monophosphate (cAMP) on phosphoinositide (PI) metabolism and associated changes of the permeability of the nervous fibers in the crustaceans Carcinum maenas and Eriphia spinifrons, as well as in the frog Rana temporaria, has been investigated. It was shown that ACh induces a significant decrease in the content of triphosphoinositides (TPI) in the nervous fibers of the crabs and increases their potassium permeability, which in its turn results in depolarization of the fibers. ACh did not affect frog nervous fibers.