[Blood serum proteins in diabetes mellitus. Euglobulin level].

Some physicochemical and immunochemical properties of blood serum euglobulins were studied in patients with diabetes mellitus with different degree of vascular lesions. Euglobulins were isolated from blood serum of normal subjects and diabetes mellitus patients by precipitation in low ionic strength dialyzing solution. As a result two euglobulin subfractions were obtained: soluble and insoluble in an isotonic saline.

[Blood serum euglobulins in diabetes mellitus and diabetic microangiopathies].

A study of serum euglobulins carried out in 26 patients with diabetes mellitus and in 14 healthy persons permitted to detect definite differences between sick and healthy individuals. In the patients with diabetes mellitus (most distinctly in those with microangiopathies) the level of soluble and insoluble in the phosphate buffer euglobulins was greater than in the healthy persons. The microprecipitation reaction and immunoelectrophoresis with the monospecific immunoglobulins (IgA, IgM and IgG) more frequent and higher titers demonstrated IgA and IgG in diabetic patients.