Publications by authors named "Lim KyungHwa"

Article Synopsis
  • * The study tracked newly diagnosed CHB patients (1,973 total) for an average of 3.1 years; only 15% received treatment, mostly with Entecavir, and there were notable occurrences of severe complications like compensated and decompensated cirrhosis and hepatocellular carcinoma.
  • * The economic impact is substantial, with annual healthcare costs averaging over 870,000 JPY (about 7,800 USD) per
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Introduction: The burden of respiratory syncytial virus (RSV), which causes acute respiratory illness, is well recognized among the pediatric population but also imposes a significant risk to the elderly (age ≥ 60) and those with underlying comorbidities. The study aimed to review the most recent data on epidemiology and burden (clinical and economic) of RSV in the elderly/high-risk populations in China, Japan, South Korea, Taiwan, and Australia.

Methods: A targeted review was conducted of English, Japanese, Korean, and Chinese language articles published from 1 January 2010 to 7 October 2020 relevant for the purpose.

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Article Synopsis
  • ExPEC is a significant cause of invasive diseases like sepsis, particularly affecting older adults and those with existing health conditions, leading to higher mortality and hospitalizations, especially in the Asia Pacific region.
  • A literature review covering studies from several Asian countries examined the epidemiology and economic impact of ExPEC-related invasive diseases among elderly or high-risk populations.
  • The findings indicated a high prevalence of ExPEC in invasive bacterial diseases, with associated increased healthcare costs and worse clinical outcomes, especially in South Korea and Australia.
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Purpose: To evaluate the cognitive and behavioral effects of topiramate (TPM) versus carbamazepine (CBZ) using efficacious doses of each drug as monotherapy for children with benign rolandic epilepsy.

Methods: A multicenter, randomized, open-label, observer-blinded, parallel-group clinical trial was conducted. TPM was introduced at a dose of 12.

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Gardenia fruit has been traditionally used as a folk medicine for centuries in Asian countries. Extraction with ethanol was used to obtain an extract (GFE) that contains two known constituents, geniposide and genipin, which were subsequently evaluated for anti-inflammatory activity. GFE, genipin, and geniposide showed acute anti-inflammatory activities in carrageenan-induced rat paw edema.

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