Publications by authors named "Lim K Toh"

Article Synopsis
  • The Omicron variant made it necessary for people to get booster shots for better protection against COVID-19.
  • Different countries have different vaccines, and some people need different boosters due to bad reactions to certain shots.
  • Researchers found that getting an mRNA vaccine as a booster leads to stronger antibody responses against the Omicron variant compared to using inactivated virus vaccines.
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Article Synopsis
  • Lower respiratory tract infection (LRTI) is the leading cause of infant mortality, with Respiratory Syncytial Virus (RSV) being a major contributing factor and currently lacks an approved vaccine, leaving palivizumab as a critical prevention option for high-risk infants.
  • A systematic review showed palivizumab significantly reduces RSV-related hospitalization rates by 39% to 78% compared to placebo, based on various clinical trials and studies across numerous countries.
  • Safety assessments showed no significant differences in adverse effects between palivizumab and placebo, indicating it is a safe option for preventing severe RSV-related complications in children.
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Background: Susceptibility to environmental carcinogenesis is the consequence of a complex interplay between intrinsic hereditary factors and actual exposure to potential carcinogenic agents. Exposure to sunlight is the primary etiological agent for basal cell carcinoma (BCC).

Aim: The aim of this study was to determine the effects of different ultraviolet (UV) doses on DNA damage in epidermal keratinocytes in vivo and to elucidate if patients with BCC are more susceptible to UV-induced DNA damage in comparison with normal healthy volunteers in response to solar simulator radiation (SSR).

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Introduction: Mycotic aneurysms are associated with high mortality rates and are managed in the local setting with extra-anatomical bypass followed by ligation, exclusion and debridement of the aneurysm. This is the first case of successful endovascular stenting in an immunocompromised patient with Salmonella mycotic aneurysm.

Clinical Picture: A middle-aged man who was HIV positive had Salmonella septicaemia.

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