Levatorplasty's role in rectal prolapse management for patients with wide pelvic hiatus: a cohort study.

Background And Aims: Rectal prolapse (RP) is a debilitating condition and can cause symptoms of fecal incontinence, obstructed defecation, incomplete evacuation of the rectum, and pain. In recent years, there has been increasing evidence that prolapse development is strongly associated with pelvic hiatus (GH) size (normal 4.5 +/- 0.

First case report on Bickerstaff brainstem encephalitis in a young adult from Syria: Bridging clinical knowledge and practice.

Bickerstaff Brainstem Encephalitis (BBE) is a rare immunologic condition characterized by CNS inflammation, presenting with ataxia, external ophthalmoplegia, altered consciousness, and quadriplegia. A 25-year-old male with no significant medical history exhibited symptoms of blurred vision, diplopia, facial numbness, and imbalance following a respiratory infection. Brain MRI revealed hyperintense lesions in the cerebral peduncle and pons on T2-weighted/FLAIR sequences but not on T1-weighted sequences, indicative of demyelination.

Developing and Testing a Two-Part Intervention: Enhancing Dementia Instruction and Tool in Home Hospice Care.

Family care partners (FCP) of persons living with dementia provide extensive care and experience significant stress. Hospice nurses and social workers seldom receive training to help FCP. This article describes the development and pilot testing of Enhancing Dementia Instruction and Tool in Home Hospice Care (EDITH-HC).

Analysis of clinical and radiographic outcomes at least 5 years after coronectomy for deeply impacted mandibular third molars.

Objective: Coronectomy is an alternative to traditional mandibular third molar extraction when the inferior alveolar nerve (IAN) is closely associated with the roots of these molars. Given the paucity of research on the long-term outcomes after coronectomy, we conducted this study to evaluate clinical and radiographic outcomes at least 5 years post-coronectomy.

Methods: This retrospective study enrolled all patients with impacted mandibular third molars treated with coronectomy at our institution who were willing to return for follow-up evaluation 5 years or more after their original procedure.

Impact of pre-operative mechanical bowel preparation in preventing post-operative anastomotic leak: A meta-analysis.

Colorectal operations are amongst the most frequently performed surgical procedures worldwide. Success of colorectal surgery is significantly influenced by occurrence of postoperative complications; Efforts are directed in detecting risk factors for these complications and trials to avoid risk factors to reduce complications rate. This study was conducted to assess the impact of mechanical bowel preparation in preventing post-operative anastomotic leakage in adult patients undergoing elective restorative colorectal surgery.

Dual-mode OCT/fluorescence system for monitoring the morphology and metabolism of laser-printed 3D full-thickness skin equivalents.

The 3D structure of native human skin is fundamental for studying skin health, diseases, wound healing, and for testing the safety of skin care products, as well as personalized treatments for skin conditions. Tissue regeneration, driven by tissue engineering, often involves creating full-thickness skin equivalents (FSE), which are widely used for developing both healthy and diseased skin models. In this study, we utilized human skin cell lines to create FSE.

808 nm diode laser in the treatment of Hidradenitis Suppurativa: a retrospective study.

Hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory disease characterized by painful lesions such as nodules, abscesses, and sinus tracts, primarily affecting intertriginous areas. Traditional treatments range from antibiotics and hormonal therapies to biologics and surgical options. Recently, lasers and light-based treatments has gained attention as a non-systemic treatment for HS, targeting hair follicles to potentially alleviate symptoms and improve quality of life.

Evaluation of the common skin diseases in patients with malignancies and the cutaneous side effects of cancer treatments.

Purpose: The diversity of skin diseases in patients with malignancies leads to diagnostic difficulties and complicate cancer treatment. Furthermore, the increasing use of chemotherapy drugs and novel treatment regimens raises the risk of the development of various cutaneous side effects and the need for dermatologists during cancer management. We investigated the skin diseases in patients with malignancies and the cutaneous side effects of cancer treatments.

Composition, medicinal values, and threats of plants used in indigenous medicine in Jawi District, Ethiopia: implications for conservation and sustainable use.

Indigenous knowledge of medicinal plants is vital to local communities and cultural heritage, particularly in Ethiopia. This study aims to document native medicinal plants in the Jawi district, including associated traditional knowledge. The study involved conducting semi-structured interviews, focus group discussions, and guided field walks with a purposefully selected 54 traditional healers.

Extremely Rare Coexistence of Peripherally Located Mucous Gland Adenoma and Pulmonary Chondroid Hamartoma.

Pulmonary mucous gland adenomas (MGAs) originating in mucous-secreting cells in the bronchi are extremely rare benign tumours. Pulmonary chondroid hamartomas (PCHs) are the most common benign neoplasms of mesenchymal origin of the lung. This study reports an unusual case where MGA and PCH coexisted in a peripheral intra-parenchymal location.

Evaluation of serum fibronectin levels and fibronectin gene polymorphism in patients receiving intravesical BCG therapy for non-muscle invasive bladder cancer and its prognostic value.

Background: Bladder cancer continues to be a significant health issue, leading to ongoing research into novel biomarkers and treatment strategies. This study aims to evaluate the potential of serum fibronectin levels and fibronectin gene polymorphisms as biomarkers for predicting the recurrence and treatment response in patients with NMIBC undergoing intravesical BCG therapy.

Methods: Between June 2022 and December 2022, data of 73 patients who applied to the Mersin University Urology Clinic due to NMIBC and were followed and treated in our clinic, receiving intravesical BCG treatment, when necessary, as well as 56 individuals without any malignancy, were prospectively examined.

Sensitive and reliable lab-on-paper biosensor for label-free detection of exosomes by electrochemical impedance spectroscopy.

A new, sensitive, and cost-effective lab-on-paper-based immunosensor was designed based on electrochemical impedance spectroscopy (EIS) for the detection of exosomes. EIS was selected as the determination method since there was a surface blockage in electron transfer by binding the exosomes to the transducer. Briefly, the carbon working electrode (WE) on the paper electrode (PE) was modified with gold particles (AuPs@PE) and then conjugated with anti-CD9 (Anti-CD9/AuPs@PE) for the detection of exosomes.

The Effects of Ionotropic GABA Receptor Blockage on the Brain in Rats with Induced Sepsis.

Encephalopathy following sepsis is defined as life-threatening organ failure due to the irregular response of the host to infection and has high mortality and morbidity rates. The present study aimed to investigate the effects of inflammation and the gamma-aminobutyric acid-A (GABA) receptor antagonist, bicuculline, on brain tissue in rats with sepsis. Sepsis was experimentally generated using lipopolysaccharide (LPS).

The effect of complex formation on the static and frequency-dependent nonlinear optical properties: A combined experimental and theoretical investigation.

A novel mixed ligand Mn(II) complex of 6-Bromopyridine-2-carboxylic acid (6Brpca) and 4,4'-dimethyl-2,2'-dipyridyl has been prepared and structurally characterized using single-crystal X-ray diffraction. The spectroscopic properties were also analyzed by using FT-IR and UV-Vis spectral techniques. The coordination complexes having transition metal ions are known to have promising optical nonlinearity behavior.

Identification of blood at simulated crime scenes using silver nanoparticles with SERS.

The analysis of substances and samples obtained from a crime scene is very important in solving forensic cases. To determine the variables involved in a crime and to expedite the investigation process, the rapid analysis of body fluids in small quantities and within environments containing diverse components is particularly necessary. For this reason, it is of great importance to analyze biological fluids with rapid, noncontaminating, nondestructive, low-cost, and accurate techniques.

The role of circulating miRNAs in the diagnosis of osteoporosis miRNAs in osteoporosis.

Objective: Osteoporosis, defined as a systemic skeletal disease, is characterized by increased bone fragility and fracture risk. Studies have shown that dysregulation of the functions of miRNAs or the mechanisms they mediate may be an important pathological factor in bone degeneration. Therefore, the aim of the study was to determine the role of miRNAs, which are thought to play a role in bone metabolism, in osteoporosis.

A potential cause for extensive dieback of plantation in highland districts of Awi zone, northwestern Ethiopia.

Although De Wild has rapidly expanded for economic and ecological purposes in the highland districts of the Awi zone, northwestern Ethiopia, recent plantations have suffered from severe defoliation, dieback, and stunted growth. We conducted this study in four districts that hold potential for plantations. The study examined the identification of the causal agent, its occurrence, and local community perceptions of the plantation's significant dieback.

Do patients with acne tend to have increased body fat? Comparison of body composition analysis of patients with acne vulgaris and healthy individuals: a prospective case control study.

Background: Acne vulgaris is a chronic, inflammatory skin disease which has been associated with metabolic syndrome and obesity. However, data on body composition in patients with acne vulgaris are scarce.

Aim: We aimed to assess body composition in patients with acne vulgaris, compare the results with those of healthy individuals, and evaluate the relationship between body composition and acne severity.