Publications by authors named "Lillie Lamont"
Article Synopsis
- Patients with chronic kidney disease (CKD) on renal replacement therapy (RRT) face a high risk of infections from cardiovascular implantable electronic devices (CIED), but device extraction, the usual way to manage these infections, is often avoided due to high procedural risks.
- A study analyzed data from CKD patients with CIED infections, finding that 30% underwent device extraction, which significantly improved one-year survival rates (59.2% vs. 48.8% for no extraction).
- Despite the survival benefits, the low rate of device extraction among these patients highlights a need for better management strategies in this high-risk group.
Prohibitins (PHBs) are a highly conserved class of proteins and have an essential role in transcription, epigenetic regulation, nuclear signaling, mitochondrial structural integrity, cell division, and cellular membrane metabolism. Prohibitins form a heterodimeric complex, consisting of two proteins, prohibitin 1 (PHB1) and prohibitin 2 (PHB2). They have been discovered to have crucial roles in regulating cancer and other metabolic diseases, functioning both together and independently.
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