Evaluation of Anti-HBs Antibody Immune Response against Hepatitis B virus in Vaccinated People in a North-eastern Bulgaria Region.

Introduction: Hepatitis B virus (HBV) is one of the most significant human pathogens responsible for a huge number of acute and chronic liver infectious diseases worldwide.

Aim: To find the duration of post-vaccination immune response in individuals allocated to five age groups from 6 months to 20 years.

Materials And Methods: All tested subjects were born between 1999 and 2018 and therefore covered by the compulsory vaccination program against hepatitis B.

Detection of EBV DNA in Non-Hodgkin Lymphoma Patients in Bulgaria.

Epstein-Barr virus is the first human oncogenic virus associated with a broad range of different malignant diseases but its role in non-Hodgkin lymphomas (NHL) development still needs to be fully understood. High expression levels of EBV major genes are found in NHL tumor cells and free viral DNA circulates in the plasma of such individuals. In the current study we detected EBV DNA levels in plasma samples from NHL patients in order to validate its significance as a laboratory marker for disease monitoring.