A continuous learning approach to brain tumor segmentation: integrating multi-scale spatial distillation and pseudo-labeling strategies.

Introduction: This study presents a novel continuous learning framework tailored for brain tumour segmentation, addressing a critical step in both diagnosis and treatment planning. This framework addresses common challenges in brain tumour segmentation, such as computational complexity, limited generalisability, and the extensive need for manual annotation.

Methods: Our approach uniquely combines multi-scale spatial distillation with pseudo-labelling strategies, exploiting the coordinated capabilities of the ResNet18 and DeepLabV3+ network architectures.

A supervised learning rule for classification of spatiotemporal spike patterns.

This study introduces a novel supervised algorithm for spiking neurons that take into consideration synapse delays and axonal delays associated with weights. It can be utilized for both classification and association and uses several biologically influenced properties, such as axonal and synaptic delays. This algorithm also takes into consideration spike-timing-dependent plasticity as in Remote Supervised Method (ReSuMe).

Application of cross-correlated delay shift rule in spiking neural networks for interictal spike detection.

This study proposes a Cross-Correlated Delay Shift (CCDS) supervised learning rule to train neurons with associated spatiotemporal patterns to classify spike patterns. The objective of this study was to evaluate the feasibility of using the CCDS rule to automate the detection of interictal spikes in electroencephalogram (EEG) data on patients with epilepsy. Encoding is the initial yet essential step for spiking neurons to process EEG patterns.

A Cross-Correlated Delay Shift Supervised Learning Method for Spiking Neurons with Application to Interictal Spike Detection in Epilepsy.

This study introduces a novel learning algorithm for spiking neurons, called CCDS, which is able to learn and reproduce arbitrary spike patterns in a supervised fashion allowing the processing of spatiotemporal information encoded in the precise timing of spikes. Unlike the Remote Supervised Method (ReSuMe), synapse delays and axonal delays in CCDS are variants which are modulated together with weights during learning. The CCDS rule is both biologically plausible and computationally efficient.

A biological plausible Generalized Leaky Integrate-and-Fire neuron model.

This study introduces a new Generalized Leaky Integrate-and-Fire (GLIF) neuron model. Unlike Normal Leaky Integrate-and-Fire (NLIF) models, the leaking resistor in the GLIF model equation is assumed to be variable, and an additional term would have the bias current added to the model equation in order to improve the accuracy. Adjusting the parameters defined for the leaking resistor and bias current, a GLIF model could be accurately matched to any Hodgkin-Huxley (HH) model and be able to reproduce plausible biological neuron behaviors.

[The impact of early surgery on long-term outcome of patients with left-sided infective endocarditis].

Objective: This study aims to evaluate the impact of early surgery on long-term outcome of patients with left-sided native valve infective endocarditis (IE).

Methods: Clinical data were retrospectively reviewed in 239 consecutive patients with left-sided native valve IE from 2002 to 2012 in Peking Union Medical College Hospital (PUMCH). Propensity score was used to match patients in the early operation and conventional treatment groups.

A generalized Leaky Integrate-and-Fire neuron model with fast implementation method.

This study introduces a new Generalized Leaky Integrate-and-Fire (GLIF) neuron model with variable leaking resistor and bias current in order to reproduce accurately the membrane voltage dynamics of a biological neuron. The accuracy of this model is ensured by adjusting its parameters to the statistical properties of the Hodgkin-Huxley model outputs; while the speed is enhanced by introducing a Generalized Exponential Moving Average method that converts the parameterized kernel functions into pre-calculated lookup tables based on an analytic solution of the dynamic equations of the GLIF model.

[Cardiac involvement of the type I mucopolysaccharidosis].

Objective: To investigate the manifestations of cardiac involvement in the patients with mucopolysaccharidosis I (MPS I).

Methods: The clinical data of 10 MPS I patients were collected. Electrocardiography (ECG) and echocardiography (Echo) were performed in all patients and then analyzed.

Effect of high-dose statin versus low-dose statin plus ezetimibe on endothelial function: a meta-analysis of randomized trials.

Background: Combining low-dose statin and ezetimibe reduces the low-density lipoprotein cholesterol (LDL-C) similar to high-dose statin. However, whether there is a difference in the effect of these 2 lipid-lowering regimes on endothelial function is still controversial.

Methods: We performed a systematic search of databases (MEDLINE [1950 to September 2011], EMBASE [1966 to September 2011]) and references of identified studies.

[Cardiovascular risk profile of patients with glycogen storage disease type I].

Objective: To investigate the cardiovascular risk profile in patients with glycogen storage disease (GSD) type I.

Method: The clinical information of 62 patients with GSD type I who admitted to Peking Union Medical Hospital were reviewed and the cardiovascular risk profile was analyzed.

Results: The age of the patient cohort was (8.

Echocardiographic characteristics of intravenous leiomyomatosis with intracardiac extension: a single-institution experience.

Background: Intravenous leiomyomatosis (IVL) is a rare smooth-muscle proliferation arising from a uterine myoma and occasionally extending into cardiac chambers.

Methods And Results: A series of 10 consecutive patients with histologically and surgically proven intracardiac IVL between 2000 and 2010 in our hospital were reviewed. The echocardiographic features of 10 cases with IVL and extensive spread into the right-sided cardiac chambers were described for the first time.

A retrospective study of congenital scoliosis and associated cardiac and intraspinal abnormities in a Chinese population.

Our objective is to assess the incidence of cardiac and intraspinal abnormities in Chinese congenital scoliosis (CS) patients and to study the relationship between the associated abnormities and the different CS types. Five-hundred and thirty-nine consecutive Chinese patients with CS were retrospectively studied, and the records of echocardiography, plain radiograph of the entire spine, magnetic resonance imaging of the entire spine and/or myelogram were reviewed. The results indicated that the incidence of cardiac and intraspinal abnormities in CS patients was 14.

Anesthetic considerations of an emergency decompressive craniotomy complicated with Ebstein's anomaly and atrial septal defect.

Despite considerable published papers regarding Ebstein's anomaly (EA) patients receiving open-heart tricuspid valve replacement, non-cardiac emergency surgeries were rarely reported. We report a case of emergency decompressive craniotomy in a patient with EA. Anesthesiologists should pay special attention to the complications and anesthetic management during the non-cardiac surgeries performed in EA patients.

[Cardiovascular manifestations in Chinese patients with hypereosinophilic syndrome].

Objective: To evaluate the cardiovascular involvements in Chinese patients with hypereosinophilic syndrome.

Method: We respectively reviewed 149 inpatients with hypereosinophilic syndrome admitted to Peking Union Medical College Hospital and analyzed the cardiovascular involvements in these patients.

Results: Cardiac abnormalities was evidenced in 32.

Magnesium transporter AtMGT9 is essential for pollen development in Arabidopsis.

Magnesium (Mg(2+)) is abundant in plant cells and plays a critical role in many physiological processes. A 10-member gene family AtMGT (also known as AtMRS2) was identified in Arabidopsis, which belongs to a eukaryote subset of the CorA superfamily, functioning as Mg(2+) transporters. Some family members (AtMGT1 and AtMGT10) function as high-affinity Mg(2+) transporter and could complement bacterial mutant or yeast mutant lacking Mg(2+) transport capability.

[Clinical and pathological characteristics of constrictive pericarditis in China].

Objective: To summarize the clinical and pathological characteristics of constrictive pericarditis in China.

Method: Data from 150 patients with constrictive pericarditis who admitted to our hospital from 2000 to 2007 were retrospectively analyzed.

Results: Constriction pericarditis was detected by echocardiography in 149 out of 150 patients.