Objectives: Humans can develop a vector-associated allergy to galactose-α-1,3-galactose (α-gal) a polysaccharide found in mammalian meats and by-products, resulting in α-gal syndrome (AGS). tick bites have been implicated in AGS development in the United States, but the AGS clinical burden in South Carolina is not well understood. Because is the predominant tick species in the state and large AGS cohorts exist in neighboring states, the potential for AGS clinical cases in South Carolina exists.
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