The inflammatory profile and liver damage of a sucrose-rich diet in mice.

Unlabelled: It is still unclear if an isoenergetic, sucrose-rich diet leads to health consequences.

Aims: To investigate the effects of excessive sucrose within an isoenergetic diet on metabolic parameters in male C57BL/6 mice.

Methods: Animals were fed a control diet (10% fat, 8% sucrose - SC group), a high-sucrose diet (10% fat, 32% sucrose - HSu group), a high-fat diet (42% fat, 8% sucrose - HF group) or a high-fat/high-sucrose diet (42% fat, 32% sucrose - HF/HSu group) for 8 weeks.