Response of masticatory muscles to treatment with orthodontic aligners: a preliminary prospective longitudinal study.

Introduction: The emergence of orthodontic aligners has provided an aesthetic and comfortable option for orthodontic treatment. However, the encapsulated design of the aligners can influence the masticatory muscles, and might compromise safe treatment.

Objective: This preliminary longitudinal study aimed to investigate whether the use of orthodontic aligners affects the biting force and myoelectric activity of the superficial masseter and anterior temporal muscles.

Beyond Usual Geographical Scales of Analysis: Implications for Healthcare Management and Urban Planning.

Introduction: In the context of climate emergency, advances in geographic information systems, geocoding, and geomedicine allow us to go beyond the conventional usual scales and be aligned with people's needs, improving knowledge and accuracy of the spatial pattern of health outcomes. This study shows that the geographical scale of analysis affects the interpretation of health outcomes.

Methods: All mortality that occurred in Portugal in 2014-2017 was geocoded.

Selection and Characterization of Single-Stranded DNA Aptamers of Diagnostic Potential against the Whole Zika Virus.

Zika virus became a major public health problem in early 2015, when cases of Guillain-Barré syndrome and microcephaly were associated with viral infection. Currently, ZIKV is endemic in all tropical areas of the world, and the chance for future Zika epidemics remains very real and accurate diagnosis is crucial. The aim of this work was to select specific ssDNA aptamers that bind to the entire Zika virus and can be used to compose specific diagnostics, without cross-reactivity with other flaviviruses.

Multimorbidity Profile of COVID-19 Deaths in Portugal during 2020.

Background: COVID-19 is caused by SARS-CoV-2 infection and has reached pandemic proportions. Since then, several clinical characteristics have been associated with poor outcomes. This study aimed to describe the morbidity profile of COVID-19 deaths in Portugal.

Human health outcomes at the neighbourhood scale implications: Elderly's heat-related cardiorespiratory mortality and its influencing factors.

The excessively warm weather, especially in cities, can lead to several adverse impacts, including heat-related mortality, becoming an increasingly important public health issue. Previous studies on heat-related mortality have assessed risk factors at the municipal scale, missing the intra-urban variability in heat risk and vulnerability. The knowledge of the spatial intra-variability can help to design spatially targeted measures to better protect citizens' health.

Escobar Syndrome-An Multidisciplinary Approach for an Excellent Outcome With 3 Years of Follow-Up.

This case report intends to provide the facial characteristics of Escobar syndrome and to describe the orthodontic treatment of a 12-year-old female patient diagnosed with it. Escobar syndrome, a variant of the multiple pterygium syndrome, is a rare disorder with many systemic, facial, and oral manifestations.The patient presented with mixed dentition, severe dolichofacial pattern, increased lower facial height, convex profile, severe anterior open bite, maxillary hypoplasia, and mandibular retrognatism.

Surface morphology changes of acrylic resins during finishing and polishing phases.

Introduction: The finishing and polishing phases are essential to improve smoothness and shining on the surface of acrylic resins used to make removable orthodontic appliances. A good surface finishing reduces roughness, which facilitates hygiene, prevents staining and provides greater comfort to the patients.

Objective: The aim of this paper was to analyze the changes on surface morphology of acrylic resins during finishing and polishing phases.

Superficial morphology and mechanical properties of in vivo aged orthodontic ligatures.

Introduction: The degradation of elastic ligatures in the oral environment results in the need of periodic replacement to maintain the optimal force during the orthodontic treatment. The purpose of this study was to perform a clinical prospective randomized study of the degradation of orthodontic elastomeric ligatures in the oral environment by scanning electron microscopy (SEM) and tensile strength test.

Methods: Two hundred elastic ligatures were randomly selected and placed around the brackets of 5 volunteers and removed in groups of 10, at different times (1, 2, 3, and 4 weeks).

Nanostructured severe plastic deformation processed titanium for orthodontic mini-implants.

Titanium mini-implants have been successfully used as anchorage devices in Orthodontics. Commercially pure titanium (cpTi) was recently replaced by Ti-6Al-4V alloy as the mini-implant material base due to the higher strength properties of the alloy. However, the lower corrosion resistance and the lower biocompatibility have been lowering the success rate of Ti-6Al-4V mini-implants.

Sequential bone healing of immediately loaded mini-implants: histomorphometric and fluorescence analysis.

Introduction: Mini-implants are often immediately loaded for orthodontic treatment; however, changes in interfacial tissues caused by early loading and its effects might compromise the mini-implant's function. The purpose of this study was to compare the healing of interfacial tissues 1, 4, and 12 weeks after the placement of titanium-alloy mini-implants in New Zealand rabbits; some of the implants were loaded immediately and others were left unloaded.

Methods: Eighteen animals were used in the experiment.

Systemic levels of metallic ions released from orthodontic mini-implants.

Introduction: Orthodontic mini-implants are a potential source of metallic ions to the human body because of the corrosion of titanium (Ti) alloy in body fluids. The purpose of this study was to gauge the concentration of Ti, aluminum (Al), and vanadium (V), as a function of time, in the kidneys, livers, and lungs of rabbits that had Ti-6Al-4V alloy orthodontic mini-implants placed in their tibia.

Methods: Twenty-three New Zealand rabbits were randomly divided into 4 groups: control, 1 week, 4 weeks, and 12 weeks.

Sequential bone healing of immediately loaded mini-implants.

Introduction: The relatively small size and the ability to load mini-implants without delay are important changes in the simplification of bone rigid anchorage. The purpose of this study was to analyze interfacial healing 1, 4, and 12 weeks after the placment of titanium mini-implants in New Zealand rabbits by removal torque test (RTT) and scanning electron microscopy (SEM).

Methods: Eighteen animals were used in the experiment, in which 72 titanium grade 5 mini-implants 2.

Titanium alloy mini-implants for orthodontic anchorage: immediate loading and metal ion release.

Removable osseointegrated titanium mini-implants were successfully used as anchorage devices in orthodontics. The early load is necessary to simplify the mini-implant methodology, but can lead to failure during osseointegration. The Ti-6Al-4V alloy was used instead of commercially pure Ti due to its superior strength.

Early infection and asymptomatic spread of hepatitis A virus in a public child care center in Rio de Janeiro, Brazil: should attending children under two years of age be vaccinated?

A cross-sectional study was conducted in order to identify hepatitis A virus (HAV) serological markers in 418 individuals (mean age, 16.4 years; range, 1 month-80 years) at a public child care center in Rio de Janeiro, Brazil, as well as to analyze risk factors and determine circulating genotypes. Serum samples were tested using an enzyme immunoassay.