Publications by authors named "Liliane Bezerra de Lima"
Evaluation of Antioxidant, Antibacterial and Enhancement of Antibiotic Action by Punica granatum Leaves Crude Extract and Enriched Fraction against Multidrug-Resistant Bacteria.
Chem Biodivers
December 2021
Article Synopsis
- The study investigated the phytochemical composition, antioxidant properties, and antimicrobial effects of different extracts from Punica granatum (pomegranate) leaves, using various extraction and analysis techniques.
- The ethyl acetate fraction (EAF) showed significant antimicrobial activity against multidrug-resistant bacteria, especially Gram-positive strains, and could enhance the effectiveness of antibiotics like ampicillin and ciprofloxacin.
- The findings suggest that combining antioxidant-rich extracts with antibiotics may provide a new therapeutic strategy to combat antibiotic resistance.
The chemical composition, the antioxidant and antimicrobial potential of crude extract from leaves and their enriched fractions was studied. Phytochemical analyses were performed by TLC and HPLC, and the antioxidant capacity was verified by DPPH and ABTS. The Minimal Inhibitory/Bactericidal Concentration was conducted against twenty-two bacteria to select five strains susceptible to extracts/fractions and resistant to the antibiotics tested.
View Article and Find Full Text PDFThe objective of this study was to conduct phytochemical characterization and biological evaluation of . Crude extracts and fractions from the bark, leaves and pods, were obtained for phytochemical screening by TLC and HPLC, and evaluation of antibacterial and antioxidant potential. Chromatographic data revealed the presence of several metabolites, notably from the flavonoid class.
View Article and Find Full Text PDF