A study of two protocols combining aglepristone and cloprostenol to treat open cervix pyometra in the bitch.

To compare the efficacy and safety of two protocols using a combination of aglepristone and cloprostenol for the treatment of open cervix pyometra in the bitch and to describe the progesterone (P4) serum profiles before and during treatments, 15 bitches were randomly allocated into two treatment groups: I (n = 8): aglepristone was administered at 10mg/kg, s.c., on Days 1, 3, 8, and 15 (if not cured), combined with cloprostenol at the dose of 1 microg/kg, s.

Use of prostaglandins and bromocriptine mesylate for pregnancy termination in bitches.

Objective: To assess the efficacy and safety of 2 protocols using bromocriptine mesylate and prostaglandins to terminate unwanted pregnancy in bitches.

Design: Prospective randomized single-blind controlled study.

Animals: 34 crossbred and purebred bitches referred for possible pregnancy termination.