Publications by authors named "Liliana Bordean"
Article Synopsis
- The study investigates primary nonresponse status (PNRS) and secondary nonresponse status (SNRS) in rheumatoid arthritis (RA) patients across different age and sex groups, highlighting the challenges in defining these conditions and their effects on patient quality of life.
- 115 RA patients were analyzed, focusing on factors like age, body mass index (BMI), and the type and duration of therapy to understand their association with PNRS and SNRS.
- Results showed that age, sex, and BMI significantly impact the development of PNRS and SNRS, with specific therapies affecting different demographics in distinct ways.
Background/aim: Chloride intracellular channel protein 1 (CLIC1) activates inflammasomes in rheumatoid (RA) and psoriatic (PsA) arthritis. We studied CLIC1 expression in RA and PsA patients' skin with vasculitis and its variability depending on the therapy used.
Materials And Methods: CLIC1 immunoexpression was evaluated in the vascular (CLIC1-V) and stromal (CLIC1-S) compartments of the RA and PsA skin biopsies of patients treated with methotrexate (MTX), leflunomid (LFN), corticotherapy (CT), or biological therapies.