A case-control study of factors associated with SARS-CoV-2 infection among healthcare workers in Colombia.

Background: Healthcare Workers (HCW) are repeatedly exposed to SARS-CoV-2 infection. The aim of this study was to identify factors associated with SARS-CoV-2 infection among HCW in one of the largest cities in Colombia.

Methods: We conducted a case-control study, where cases had a positive reverse transcription-polymerase chain reaction and controls had a negative result.

Effect of vaccination against oral HPV-16 infection in high school students in the city of Cali, Colombia.

Introduction: In recent years, an association between HPV-16 and oropharyngeal cancers has been reported. Therefore, it is necessary to evaluate whether vaccination decreases the exposure of HPV-16 in the oral cavity.

Objective: To evaluate the effect of vaccination on oral HPV-16 infection in high school students in the city of Cali, Colombia.

Interaction between DNA and Drugs Having Protonable Basic Groups: Characterization through Affinity Constants, Drug Release Kinetics, and Conformational Changes.

This paper reports the in vitro characterization of the interaction between the phosphate groups of DNA and the protonated species of drugs with basic groups through the determination of the affinity constants, the reversibility of the interaction, and the effect on the secondary structure of the macromolecule. Affinity constants of the counterionic condensation DNA-drug were in the order of 10⁶. The negative electrokinetic potential of DNA decreased with the increase of the proportion of loading drugs.