Publications by authors named "Lilian Torres-Tobar"
Article Synopsis
- The study investigates the genetic factors linked to severe COVID-19, specifically focusing on hospitalized cases in admixed Americans.
- Researchers conducted the largest genome-wide association study (GWAS) for COVID-19 hospitalization in this population, identifying four significant genetic associations, including two novel loci found in Latin Americans.
- The findings highlight the importance of including diverse populations in genomic research, aiming to improve understanding of genetic risks associated with COVID-19 across different ethnic groups.
Article Synopsis
- A genome-wide study involving nearly 12,000 COVID-19 positive cases in Spain identified significant genetic variants linked to hospitalization, with specific loci associated with males (3p21.31, 21q22.11) and females (9q21.32 near TLE1).
- A second phase combined data with an additional cohort, revealing two new risk loci (9p13.3, 19q13.12) related to candidate genes AQP3 and ARHGAP33, and confirmed earlier findings in males for some loci.
- The analysis highlighted genetic differences in COVID-19 severity between sexes and ages, with more pronounced heritability in males, particularly those over
Article Synopsis
- The study investigates how the Apoϵ gene, particularly the ϵ4 allele, interacts with cardio-metabolic and social risk factors in relation to cognitive impairment in Bogotá's elderly population.
- It analyzed 1,263 participants over 50 years old, categorizing them into groups based on their cognitive status and Apoϵ allele presence.
- Results indicated that while lower education, high blood pressure, and older age were associated with dementia, the ϵ4 allele mainly affected diabetic individuals with dementia, who tended to score lower on cognitive tests.
Purpose: Zika virus (ZIKV) infection is an emerging global threat and a public health problem in the Americas. Guillain-Barré syndrome (GBS) has been recently associated to ZIKV. This report presents a case series of GBS possibly associated to ZIKV.
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