Publications by authors named "Lilian P Barbeta"
Article Synopsis
- Researchers found that specific gene expressions in oral squamous cell carcinoma (OSCC) tumors can predict whether lymph nodes are compromised, which helps in determining treatment strategies.
- They identified four key genes using techniques like RT-PCR to build a "Nodal Index" (NI) based on their expression in tumors from two patient groups, effectively distinguishing between lymph node positive and negative cases.
- The Nodal Index showed high accuracy—88.6% in a learning group and 80% in an independent validation group—indicating its potential as a reliable tool for predicting lymph node metastasis in OSCC patients, regardless of tumor size and grade.
