Publications by authors named "Lilian C A Silva"
Spatiotemporal transmission of SARS-CoV-2 lineages during 2020-2021 in Pernambuco-Brazil.
Microbiol Spectr
June 2024
SARS-CoV-2 virus emerged as a new threat to humans and spread around the world, leaving a large death toll. As of January 2023, Brazil is among the countries with the highest number of registered deaths. Nonpharmacological and pharmacological interventions have been heterogeneously implemented in the country, which, associated with large socioeconomic differences between the country regions, has led to distinct virus spread dynamics.
View Article and Find Full Text PDFReal-life evaluation of a rapid antigen test (DPP SARS-CoV-2 Antigen) for COVID-19 diagnosis of primary healthcare patients, in the context of the Omicron-dominant wave in Brazil.
Clin Microbiol Infect
March 2023
Article Synopsis
- The study evaluated the effectiveness of a rapid antigen test for diagnosing COVID-19 during an Omicron wave in Brazil, involving 347 individuals from a public testing center.
- The rapid test showed an overall sensitivity of 80.5% and a high specificity of 99.2%, with performance varying based on viral load levels (higher sensitivity with lower Ct values).
- The results suggest that the rapid antigen test is a reliable option for COVID-19 diagnosis in situations where PCR testing may be limited, especially in areas with high disease prevalence.
DNA methylation is one of the mechanisms of epigenetic regulation and is observed in mammals to maintain a normal expression pattern of the genes. Aberrant profiles of DNA methylation have already been associated with cardiovascular diseases. We evaluated 190 patients with Acute Coronary Syndrome (ACS) and 75 patients without ACS (non-ACS).
View Article and Find Full Text PDFAcute coronary syndrome: Relationship between genetic variants and TIMI risk.
Cytokine
October 2018
Acute Coronary Syndrome (ACS) is a multifactorial disease, including the genetic factor, caused by coronary artery obstruction by atheroma. Some genetic variants have been described as risk factors for this disease. Its early diagnosis and stratification of risk of death by Thrombolysis in Myocardial Infarction (TIMI) are important.
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