Publications by authors named "Lilia M Velez-Velez"
Article Synopsis
- Parkinson's disease (PD) is a neurodegenerative disorder associated with abnormal protein clumping and faulty protein regulation, prompting this study to analyze gene expression in a Mexican-Mestizo PD group compared to healthy individuals.
- The research involved 87 PD patients and 87 controls, revealing significant downregulation of specific genes in the PD group, which correlates with the disease's presence.
- A newly developed gene expression model based on these findings shows potential for accurately diagnosing early-stage PD, highlighting a notable connection between reduced gene expression and the condition in the studied population.
Background: Depressive disorders are common during pregnancy. There is compelling evidence that the inflammatory response system is important in the pathophysiology of depression. Higher concentrations of proinflammatory cytokines including tumor necrosis factor-alpha (TNF-α) in depressed subjects have been described.
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