Publications by authors named "Lili Peng"

Background: Thyroid nodule rupture (TNR) is a rare and severe complication after thermal ablation (TA), mostly from benign thyroid nodules (BTN).

Objective: To summarize the incidence of TNR after TA and analyze the causes and prevention strategies.

Materials And Methods: This retrospective study enrolled 3971 patients who underwent TA for BTN from January 2014 to March 2024.

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  • The study aimed to assess how different levels of thyroid-stimulating hormone (TSH) affect tumor progression and survival in patients with early-stage papillary thyroid cancer treated with microwave ablation (MWA).
  • It analyzed the medical records of 525 patients, categorizing them into uni-focal (U-PTC) and multifocal (M-PTC) groups based on TSH levels after treatment, and observed the rates of tumor progression and survival outcomes.
  • Results indicated that lower TSH levels in U-PTC patients correlated with higher tumor progression rates and reduced progression-free survival compared to medium and high TSH levels, whereas M-PTC patients showed no significant relationship between TSH levels and progression.
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Objectives: This study aimed to evaluate the long-term efficacy and safety of microwave ablation (MWA) for solitary T1N0M0 papillary thyroid carcinoma (PTC) and compare them between T1a and T1b disease.

Materials And Methods: This retrospective study included 136 patients with solitary T1N0M0 PTC who were treated with MWA and followed up for more than 5 years. Outcomes were compared between patients with T1a and T1b disease.

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Photobiomodulation (PBM) is a safe and effective neurotherapy that modulates cellular pathways by altering cell membrane potentials, leading to beneficial biological effects such as anti-inflammatory and neuroregenerative responses. This review compiles studies from PubMed up to March 2024, investigating the impact of light at wavelengths ranging from 620 to 1270 nm on ion channels. Out of 330 articles screened, 19 met the inclusion criteria.

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  • Thermal ablation (TA) is an effective treatment for benign thyroid nodules (BTNs), but the study seeks to determine the optimal maximum diameter (MD) for effective results.
  • Analyzing data from 639 BTNs, the study finds that the complete disappearance rate is significantly linked to the MD, with an optimal threshold identified at 25.0 mm.
  • Results show that BTNs larger than 25.0 mm have a lower chance of complete disappearance and a higher rate of complications compared to smaller nodules.
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  • The study aimed to evaluate the feasibility, efficacy, and safety of microwave ablation for treating follicular thyroid neoplasms.
  • It involved 74 patients, achieving a 100% technical success rate and significant reduction in nodule size and volume over 24 months, with no adverse changes in thyroid function.
  • Results indicate that microwave ablation is an effective and safe treatment option, with low rates of recurrence and complications.
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Objective: To evaluate the efficacy and safety of thermal ablation in treating solitary low-risk T2N0M0 papillary thyroid cancer (PTC) and compare the outcomes of microwave ablation (MWA) and radiofrequency ablation (RFA).

Materials And Methods: This retrospective, single center study involved 34 patients (age: 40.0 ± 13.

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Introduction: Prone positioning in critical care units may reduce mortality in specific patients who have been admitted with severe conditions.

Aim: The current meta-analysis aims to assess the impact of prone compared to supine position besides the safety and tolerability of different enteral feeding techniques in critically ill patients regarding mortality, pneumonia, aspiration, and vomiting.

Material And Methods: A systematic literature search found 25 relevant trials involving 1984 participants at the start of the study.

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  • * A retrospective analysis of 280 TR5 nodules revealed that larger nodules (MD ≥ 6.2 mm) were more likely to yield probably malignant (PM) outcomes compared to smaller ones, with a significant difference in MD between PM and probably benign (PB) groups.
  • * The findings suggest that an MD threshold of 6.2 mm is optimal for deciding when to perform FNA in TR5 nodules, as larger nodules have a higher probability
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Background Microwave ablation (MWA) is currently under preliminary investigation for the treatment of multifocal papillary thyroid carcinoma (PTC) and has shown promising treatment efficacy. Compared with surgical resection (SR), MWA is minimally invasive and could preserve thyroid function. However, a comparative analysis between MWA and SR is warranted to draw definitive conclusions.

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  • * The patient, a 77-year-old male, was initially treated for prostate cancer with radiation and endocrine therapy, but later developed rectal DLBCL with lung metastases seven years after the prostate cancer diagnosis.
  • * The case highlights the importance of recognizing the possibility of coexisting cancers, even though it is uncommon, which can enhance understanding of cancer progression and treatment.
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Background: In recent investigations, substantial strides have been made in the precise modulation of the gut microbiota to prevent and treat a myriad of diseases. Simultaneously, the pressing issue of widespread antibiotic resistance and multidrug resistance resulting from infections demands urgent attention. Several studies suggest that the antagonistic influence of the gut microbiota could serve as a novel avenue for impeding the colonization of pathogenic microorganisms or treating infections.

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Subglottic masses is very rare. The clinical data of five cases of subglottic mass in our hospital from 2017 to 2022 were summarized, and their clinical manifestations, auxiliary examination findings, treatment plan and pathological features were analyzed. Among the 5 patients, 1 case was subglottic pleomorphic adenoma, 1 case was subglottic granuloma, 1 case was subglottic breast cancer metastasis, 1 case was subglottic primary adenoid cystic carcinoma, and 1 case was immunoglobulin G4-related disease.

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Background: Notwithstanding a plethora of observational studies, the causal implications of obesity, encompassing both body mass index (BMI) and waist circumference (WC), as well as type 2 diabetes (T2D), and lifestyle factors, in relation to the vulnerability to low back pain (LBP), remain enigmatic.

Aims: This study was designed to investigate the related causal associations DESIGN: A two-sample Mendelian randomization (MR) analysis.

Settings: By utilizing genetic variants associated with pertinent factors gleaned from genome-wide association studies (GWASs), We extracted independent genetic variants about exposures such as BMI, WC, T2D, smoking, alcohol consumption, and coffee intake from published GWASs, ensuring their genome-wide significance.

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Objective: To evaluate the complications associated with microwave ablation (MWA) in treating persistent/recurrent hyperparathyroidism (HPT) post-surgical or ablative treatments.

Materials And Methods: From January 2015 to December 2022, 87 persistent/recurrent HPT patients (primary HPT [PHPT]: secondary HPT [SHPT] = 13:74) who underwent MWA after surgical or ablative treatment were studied. Grouping was based on ablation order (initial vs.

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Rationale And Objectives: To evaluate the feasibility, efficiency, and safety of microwave ablation (MWA) for multifocal papillary thyroid microcarcinoma (PTMC).

Methods: This was a retrospective study, and the data of patients who underwent MWA for multifocal PTMC from October 2016 to December 2021 were reviewed. After ablation, the changes in tumor size and volume, as well as the rates of technical success, tumor disappearance, disease progression, and complications, were assessed.

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Objectives: To explore the relationship between arytenoid cartilage sclerosis and a history of previous surgical resection in patients with laryngeal contact granuloma.

Methods: 167 patients with laryngeal contact granuloma treated from March 2016 to December 2018 were studied. The high-resolution computed tomography (HRCT) data of the sclerosis of arytenoid cartilage is divided into asymmetric sclerosis, bilateral sclerosis, and no sclerosis according to the range of sclerosis.

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  • - The study aims to compare the health-related quality of life (HRQoL) between patients with T1N0M0 papillary thyroid carcinoma who underwent microwave ablation (MWA) and those who had total thyroidectomy (TT).
  • - Researchers analyzed 180 patients, equally divided into two groups, using quality of life questionnaires (EORTC QLQ-C30 and THYCA-QoL) to assess HRQoL scores.
  • - Results showed that the MWA group had significantly better quality of life scores in multiple areas compared to the TT group, suggesting MWA could be a favorable alternative to TT for these patients.
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Background: The COVID-19 pandemic has exacerbated the trends of childhood overweight, obesity, and malnutrition, as well as increased psychological stress and family conflicts among family members. It is important to explore the relationship between changes in the family environment during the COVID-19 on child nutrition.

Objective: This study aims to analyze the nutritional status of Chinese children during the COVID-19 pandemic and its relationship with family diet, family environment, and parental anxiety, in order to provide evidence for further interventions in children's nutritional status.

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  • The study aimed to evaluate the safety of a new hydrodissection technique during microwave ablation (MWA) for secondary hyperparathyroidism (SHPT) by comparing improved hydrodissection to traditional methods.
  • Data from 337 patients revealed that the risk of hoarseness, a common complication from nerve injury, was significantly lower in the improved hydrodissection group (6.9%) versus the traditional group (13.0%).
  • Additionally, patients in the improved group recovered from hoarseness in a median time of 2 months compared to 6 months for those in the traditional group, suggesting the improved technique is safer without compromising technical effectiveness.
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  • The study investigates the safety and efficacy of microwave ablation (MWA) in patients with multifocal papillary thyroid carcinoma (M-PTC) compared to those with unifocal papillary thyroid carcinoma (U-PTC), using data from 504 patients over five years.
  • Results showed that while the complete ablation was achieved in all cases, the tumour disappearance rate was significantly lower and slower for M-PTC patients compared to U-PTC, but the overall safety and complication rates were comparable between the two groups.
  • In conclusion, MWA is an effective and safe treatment for selected M-PTC patients, with clinical outcomes similar to those with U-PTC
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Speckle-type pox virus and zinc finger (POZ) protein (SPOP), a substrate recognition adaptor of cullin-3 (CUL3)/RING-type E3 ligase complex, is investigated for its role in cardiac fibrosis in our study. Cardiac fibroblasts (CFs) activation was achieved with TGF-β1 (20 ng/mL) and MI mouse model was established by ligation of the left anterior descending coronary, and lentivirus was employed to mediate interference of SPOP expression. SPOP was increased both in fibrotic post-MI mouse hearts and TGF-β1-treated CFs.

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  • The study aimed to evaluate the safety and effectiveness of a new hydrodissection technique during microwave ablation for treating papillary thyroid carcinoma (PTC).
  • Data from 341 patients were analyzed, comparing traditional hydrodissection with an improved method targeting perithyroidal fascial spaces, focusing on complications and recovery outcomes.
  • The improved technique resulted in fewer cases of hoarseness due to nerve injury and a quicker recovery time, while both methods showed no significant difference in tumor disappearance rates or local recurrence during follow-up.
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