Shuffle Attention-Based Pavement-Sealed Crack Distress Detection.

To enhance the detection of pavement-sealed cracks and ensure the long-term stability of pavement performance, a novel approach called the shuffle attention-based pavement-sealed crack detection is proposed. This method consists of three essential components: the feature extraction network, the detection head, and the Wise Intersection over Union loss function. Within both the feature extraction network and the detection head, the shuffle attention module is integrated to capture the high-dimensional semantic information of pavement-sealed cracks by combining spatial and channel attention in parallel.

Identification of SMC2 and SMC4 as prognostic markers in breast cancer through bioinformatics analysis.

Background: Breast cancer (BRCA) is one of the most common malignant tumors. The structural maintenance of chromosome (SMC) gene family has been shown to play an important role in human cancers. However, the role of SMC families in BRCA is unclear.

Characteristics and factors influencing hypothalamic pituitary dysfunction in patients with craniopharyngioma.

Background: Craniopharyngioma is a benign tumor originating from the sellar region. Damages in this area caused by the tumor itself, surgery, or radiotherapy may result in severe hypothalamic-pituitary dysfunction (HPD) and eventually lead to a significant impairment in the long-term quality of life of patients. This study aimed to investigate the characteristics of HPD in patients with adamantinomatous craniopharyngioma (ACP) or papillary craniopharyngioma (PCP) and to identify the factors affecting HPD after surgery.

Automatic Pavement Crack Detection Transformer Based on Convolutional and Sequential Feature Fusion.

To solve the problem of low accuracy of pavement crack detection caused by natural environment interference, this paper designed a lightweight detection framework named PCDETR (Pavement Crack DEtection TRansformer) network, based on the fusion of the convolution features with the sequence features and proposed an efficient pavement crack detection method. Firstly, the scalable Swin-Transformer network and the residual network are used as two parallel channels of the backbone network to extract the long-sequence global features and the underlying visual local features of the pavement cracks, respectively, which are concatenated and fused to enrich the extracted feature information. Then, the encoder and decoder of the transformer detection framework are optimized; the location and category information of the pavement cracks can be obtained directly using the set prediction, which provided a low-code method to reduce the implementation complexity.

Benefits and risks evaluation of recombinant human growth hormone replacement therapy in children with GHD after craniopharyngioma surgery.

Objectives: Childhood-onset craniopharyngiomas (CPs) have a high incidence of growth hormone deficiency (GHD) leading to growth failure and metabolic disorders. We aim to evaluate the benefits and risks of recombinant human growth hormone replacement therapy (GHRT) in postoperative children.

Methods: We retrospectively analyzed auxological and metabolic parameters and adverse events before and after GHRT of 44 children after CP surgery.

Super-Resolution Reconstruction Method of Pavement Crack Images Based on an Improved Generative Adversarial Network.

A super-resolution reconstruction approach based on an improved generative adversarial network is presented to overcome the huge disparities in image quality due to variable equipment and illumination conditions in the image-collecting stage of intelligent pavement detection. The nonlinear network of the generator is first improved, and the Residual Dense Block (RDB) is created to serve as Batch Normalization (BN). The Attention Module is then formed by combining the RDB, Gated Recurrent Unit (GRU), and Conv Layer.

Evaluate Pavement Skid Resistance Performance Based on Bayesian-LightGBM Using 3D Surface Macrotexture Data.

The lack of skid resistance performance is a crucial factor leading to road traffic accidents. The pavement surface friction is an essential indicator for measuring the skid resistance. The surface texture structure significantly affects the friction between the tire and the pavement, determining the pavement skid resistance.

A Driver Gaze Estimation Method Based on Deep Learning.

Car crashes are among the top ten leading causes of death; they could mainly be attributed to distracted drivers. An advanced driver-assistance technique (ADAT) is a procedure that can notify the driver about a dangerous scenario, reduce traffic crashes, and improve road safety. The main contribution of this work involved utilizing the driver's attention to build an efficient ADAT.

Bacteriological Investigation and Drug Resistance Analysis of Chronic Refractory Wound Secretions.

Background: Chronic refractory wounds were common and the treatments were complicated for burn and plastic surgeons. This study was to investigate the bacterial distribution characteristics and bacterial drug resistance of chronic refractory wound secretions.

Methods: The authors retrospectively analyzed 425 patients with chronic refractory wound infection.

Improved Camshift object tracking algorithm in occluded scenes based on AKAZE and Kalman.

Camshift algorithm tracking is susceptible to interference when a tracking object is occluded or when its hue is similar to the background. An improved Camshift object-tracking algorithm combining AKAZE (Accelerated-KAZE) feature matching and Kalman filtering is proposed. First, the video channel is converted for processing.

Safety and efficacy of remimazolam compared with propofol in induction of general anesthesia.

Background: Remimazolam is a new ultrashort acting benzodiazepine anesthetic which has predictable sedative duration and rapid recovery in gastrointestinal endoscopy. Propofol is a commonly used intravenous anesthetic in clinical work which also has rapid action, short action time and rapid recovery. To date, there have been relatively few articles comparing the two for general anesthesia induction.

The retention of prion protein in the endoplasmic reticulum prevents N2A cells from proteasome inhibition-induced cytotoxicity.

Prion disease is a fatal neurodegenerative disease that may result from the conversion of normal cellular prion protein (PrP) to the pathogenic scrapie PrP isoform (PrP), however, how proliferation of prion leads to neuronal apoptosis is still not clear. In this study, to explore the role of the endoplasmic reticulum (ER) in prion diseases, we engineered the KDEL ER-retention motif to the C-terminus of PrP and studied its effect on N2A cell toxicity. The KDEL retention signal led to the accumulation of PrP in the ER, and KDEL signal could effectively deplete PrP from the cell surface and trap PrP in the ER/Cis-Golgi compartment.

Generation and characterization of human B lymphocyte stimulator blocking monoclonal antibody.

The cytokine, B lymphocyte stimulator (Blys) is essential for activation and proliferation of B cells and is involved in the pathogenesis of B-cell mediated autoimmune diseases. Based on its essential activity, Blys may be a potential therapeutic target for human autoimmune diseases. In this article, we have described the development of a novel humanized anti-Blys antibody, NMB04, that binds with high affinity and specificity to both soluble and membrane bound Blys.

[Molecular cloning, in vitro expression and bioactivity of TRAIL (TNFSF10) gene from finless porpoises].

To construct soluble TNF related apoptosis inducing ligand (TRAIL) expression system and investigate the effect of the expression product on tumor cell. It may provide valuable information for research into the immune system of the finless porpoise. The full-length cDNA of TRAIL (designated fTRAIL) was cloned from the total RNA of the finless porpoises blood using RT-PCR techniques and then the extracellular soluble fragments of fTRAIL (designated fsTRAIL) was ligated into pET43.

Molecular structure, expression pattern and functional characterisation of APRIL in an aquatic mammal.

The Yangtze finless porpoise (Neophocaena phocaenoides asiaorientalis) is listed on the First Order of Protected Animals in China and was identified as an endangered species by the International Union for Conservation of Nature and Natural Resources (IUCN) in 2011. A proliferation inducing ligand (APRIL), belonging to the tumour necrosis factor (TNF) family, is critical for immune regulation. In this study, we identified a finless porpoise APRIL cDNA (fAPRIL) by RACE (rapid amplification of cDNA ends) strategies, from the Yangtze finless porpoise (fAPRIL).

Molecular cloning, expression, bioinformatics analysis and bioactivity characterization of TNF13B (BAFF) gene in bat (Vespertilio superans Thomas).

B cell activating factor (BAFF) belonging to the tumor necrosis factor (TNF) family is critical to B cell survival, proliferation, maturation, and immunoglobulin secretion and to T cell activation. In the present study, the full-length cDNA of BAFF (designated bBAFF) from the bat (Vespertilio superans Thomas) was cloned using RT-PCR and rapid amplification of cDNA ends (RACE) techniques. The full-length cDNA of bBAFF consists of 986 bases including an 873 bp open reading frame encoding 290 amino acids.

[Tissue culture effect of different size explants of Lycoris aurea].

Objective: To solve the puzzle about the right size of the explant of wild medicinal plant Lycoris aurea for tissue culture.

Methods: Three-size explants: 9.0 x 8.