Publications by authors named "Lilei Lei"
Article Synopsis
- - A 60-year-old woman experienced tongue temperature perception abnormality after taking agomelatine, a medication for depression, following her initial treatment with sertraline and oxazepam.
- - She reported symptoms like emotional depression, irritability, and insomnia, which led to the switch in medications due to poor sleep quality.
- - After developing discomfort and abnormal temperature sensations, resulting in burns and blisters, she switched to duloxetine which improved her symptoms, highlighting agomelatine's potential adverse effects and the need for careful monitoring in treatment.
Background: Depression is a common psychiatric disorder with limited effective treatments. Research suggests that depression involves apoptosis mechanisms. Quercetin (QUE) has been reported to have anti-apoptotic activities.
View Article and Find Full Text PDFDepression is a clinically common and easily overlooked mental disease. Quercetin is a flavonoid compound, which has anti-inflammatory and antioxidant roles. Previous reports presented the anti-depressant role of quercetin.
View Article and Find Full Text PDFBrain ischemia is an independent risk factor for Alzheimer's disease (AD); however, the mechanisms underlining ischemic stroke and AD remain unclear. The present study aimed to investigate the function of the ε isoform of protein kinase C (PKCε) in brain ischemia-induced dendritic spine dysfunction to elucidate how brain ischemia causes AD. In the present study, primary hippocampus and cortical neurons were cultured while an oxygen-glucose deprivation (OGD) model was used to simulate brain ischemia.
View Article and Find Full Text PDFObjective: To investigate macroprolactinemia caused by antipsychotics and its clinical significance.
Methods: A total of 133 patients with schizophrenia were selected, all of whom were treated with either risperidone or amisulpride alone. The levels of total prolactin (T-PRL) and macroprolactin (MPRL) were measured before treatment as well as the second, fourth, and sixth weeks of treatment.