Publications by authors named "Likitha M J"
Background Acute coronary syndrome (ACS) is a result of the interplay between genetic and environmental risk factors. A unique cytokine macrophage migration inhibitory factor (MIF), expressed by inflammatory cells, acts via a cluster of differentiation 74 (CD74) and a cluster of differentiation 44 (CD44) receptors, leading to the recruitment of mononuclear neutrophils and lymphocytes. This cascade results in exaggerated inflammation and atherosclerosis.
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- STEMI is a serious type of heart attack caused by blocked coronary arteries due to blood clots formed from atherosclerotic plaques, and the TIMI risk score helps predict patient outcomes.
- A study with 76 MI patients focused on 50 STEMI patients, calculating their neutrophil-to-lymphocyte ratio (NLR) to assess prognosis and comparing it with their TIMI-STEMI scores.
- Results showed that most patients had a high NLR (Category C) with a mean age of 55, primarily presented with chest pain, and smoking was identified as the most common risk factor among all categories.