Postoperative body weight change and its influencing factors in patients with gastric cancer.

Background: The high incidence and mortality of gastric cancer (GC) pose a significant threat to human life and health, and it has become an important public health challenge in China. Body weight loss is a common complication after surgical treatment in patients with GC and is associated with poor prognosis and GC recurrence. However, current attention to postoperative weight change in GC patients remains insufficient, and the descriptions of postoperative weight change and its influencing factors are also different.

LncRNA Gas5 regulates Fn1 deposition via Creb5 in renal fibrosis.

Although studies on lncRNAs in renal fibrosis have focused on target genes and functions of lncRNAs, a comprehensive interaction analysis of lncRNAs is lacking. Differentially expressed genes in renal fibrosis were screened, and the interaction between lncRNAs and miRNAs was searched. We constructed a ceRNA network associated with renal fibrosis, by which we found the transcription factor Creb5, a target gene of lncRNA Gas5 that might regulate extracellular Fn1 deposition.

Slit2/Robo1 Mitigates DSS-induced Ulcerative Colitis by Activating Autophagy in Intestinal Stem Cell.

Ulcerative colitis (UC) is a recurrent intestinal inflammatory disease. Slit2, a secreted protein, interacts with its receptor Robo1 to regulate the differentiation of intestinal stem cells and participate in inflammation and tumor development. However, whether Slit2/Robo1involved in the pathogenesis of UC is not known.

Shock initiation of multi-component insensitive PBX explosives: Experiments and MC-DZK mesoscopic reaction rate model.

To facilitate the pre-estimation and optimization of the prescription design of a multi-component polymer bonded explosive (PBX), a multicomponent mesoscopic reaction rate model (MC-DZK model) is developed to predicate preferably the influence of both the explosive components and the particle size of on the shock initiation. All the parameters in the model are determined directly by the parameters in the DZK model for each explosive component. Furthermore, for the multicomponent insensitive explosive PBXC10 (70% TATB, 25% HMX, and 5% Kel-F800 by weight) with different explosive particle sizes, both shock initiation experiments and corresponding numerical simulations are performed, and there is satisfactory agreement between the numerical results and the available experimental data.

Determination of thiols in urinary sample by capillary-column liquid chromatography with amperometric detection at a carbon electrode.

The fabrication and application of an end-column amperometric detection (AD) system with a carbon electrode for capillary-column liquid chromatography (CLC) were described. This new amperometric detector showed good sensitivity and stability in detecting the thiocompounds and other analytes with CLC. In order to obtain the better separation and detection performance for analytes, several operational parameters had been investigated: the working potentials, pH and flow rate.

Quantitative determination of Freon gas using an electronic nose.

This paper reports a quantitative electronic nose (enose) for the quantitative determination of Freon gas within the concentration range 0-1000 ppm in the presence of interfering gases such as water, lubricant and petrol vapours. This quantitative enose is a new type of Freon detection system, composed of an array of four sensors. The artificial neural network (ANN) and fuzzy logic type of ANN (FNN), in combination with the relative error concept in analytical chemistry, are integrated for both quantification and discrimination.