Publications by authors named "Lijian Fang"
Article Synopsis
- The study investigates acute macular neuroretinopathy (AMN), a rare retinal disease potentially linked to COVID-19, focusing on its clinical features after infection.
- Conducted as a retrospective cohort study, it involved 66 patients diagnosed with AMN post-COVID-19, examining factors like age, gender, medical history, and symptoms.
- Key findings revealed that most patients were women, with common symptoms including scotomas, and various retinal disruptions observed through diagnostic imaging.
Aim: To investigate whether retinal nerve fiber layer defects (RNFLDs) is a potential risk factor for chronic kidney disease (CKD) in Chinese adults.
Methods: The Kailuan Eye Study was a population-based study that included 14 440 participants. All participants underwent detailed assessments, RNFLDs were diagnosed using color fundus photographs.
The gut microbiome is an important and the largest endocrine organ linked to the microbes of the GI tract. The bacterial, viral and fungal communities are key regulators of the health and disease status in a host at hormonal, neurological, immunological, and metabolic levels. The useful microbes can compete with microbes exhibiting pathogenic behavior by maintaining resistance against their colonization, thereby maintaining eubiosis.
View Article and Find Full Text PDFArticle Synopsis
- Diabetic macular edema (DME) is a serious eye condition linked to diabetes that can lead to vision loss, with treatments like pars plana vitrectomy (PPV) and internal limiting membrane (ILM) peeling being used to improve outcomes.
- A study involving 81 patients compared the effects of PPV alone versus PPV combined with ILM peeling, finding that the combination treatment led to significantly better improvements in central macular thickness, best-corrected visual acuity, and cystoid macular edema volume after surgery.
- Both groups experienced similar rates of complications post-surgery, indicating that while the combined approach may enhance visual outcomes, it does not increase the risk of adverse effects.
Aim: To investigate the risk and protective factors associated with the retinal nerve fiber layer defect (RNFLD) in a Chinese adult population.
Methods: This study was a cross-sectional population-based investigation including employees and retirees of a coal mining company in Kailuan City, Hebei Province. All the study participants underwent a comprehensive systemic and ophthalmic examination.
This study aimed to investigate the prevalence of age-related macular degeneration (AMD) in patients with diabetes mellitus (DM) and diabetic retinopathy (DR) and analyze whether DR is a risk factor for AMD. This population-based epidemiological study included 14,440 people from the Kailuan Eye Study in 2016, of whom 1,618 were patients with type 2 DM aged over 50 years, and 409 had DM with DR. We analyzed whether there were differences in the prevalence of AMD between DM with DR and DM without DR, and conducted a hierarchical statistical analysis according to different stages of DR.
View Article and Find Full Text PDFImportance: The lack of experienced ophthalmologists limits the early diagnosis of retinal diseases. Artificial intelligence can be an efficient real-time way for screening retinal diseases.
Objective: To develop and prospectively validate a deep learning (DL) algorithm that, based on ocular fundus images, recognizes numerous retinal diseases simultaneously in clinical practice.
Aim: To elucidate a simple method for isolating endothelial progenitor cells (EPCs) from human umbilical cord blood mononuclear cells and observe the endothelial cell-specific expression profile during proliferation and differentiation in vitro.
Methods: Human umbilical cord blood were isolated by Percoll density gradient centrifugation from human cord blood and cultured in vitro. The adherent cells were then identified by immunohistochemical staining and flow cytometric analysis.