Silver nanoclusters capped silica nanoparticles as a ratiometric photoluminescence nanosensor for the selective detection of I and S.

A novel and efficient approach has been established for the synthesis of silver nanoclusters capped silica nanoparticles (SiO@AgNCs). These nanoclusters (AgNCs) capped silica nanoparticles were utilized as a novel ratiometric photoluminescence (PL) nanosensor for extremely sensitive and selective detection of I and S ions. The AgNCs were prepared in situ on the silica nanoparticles through polyethyleneimine (PEI) template approach.

Label-free fluorescence turn-on detection of microRNA based on duplex-specific nuclease and a perylene probe.

A novel fluorescence turn-on microRNA (miRNA) detection method based on duplex-specific nuclease (DSN) and a perylene probe is presented in this study. A positively charged perylene derivative (compound 1) was used as the fluorescent probe. Compound 1 exhibits strong monomer fluorescence in an aqueous buffer solution.

Aminophenylboronic-acid-conjugated polyacrylic acid-Mn-doped ZnS quantum dot for highly sensitive discrimination of glycoproteins.

Discrimination of glycoproteins with different glycans is a significant but difficult issue. We presented here a new strategy for strengthening the discrimination of glycoproteins by introducing a new signaling channel, fluorescence polarization (FP), into a "single probe with three signaling channels" sensor array. The single probe was aminophenylboronic-acid-conjugated poly(acrylic acid)-Mn-doped ZnS quantum dots, and the three signaling channels were FP, room temperature phosphorescence and light scattering.