Aim: This study aimed to assess the cognitive development of individuals with congenital hypothyroidism.
Methods: Using hospital records, we identified 180 patients with congenital hypothyroidism born between 1980 and 2018 in Turku and Kuopio University Hospital catchment areas. Cognitive development was evaluated in 22 adults (7 males and 15 females) and 20 children (8 males and 12 females) using age-specific Wechsler Intelligence Scales.
J Clin Endocrinol Metab
December 2007
Context: Leptin and C-reactive protein (CRP) concentrations are increased in inflammation, and both have been linked to increased risk for cardiovascular diseases.
Objective: The objective of the study was to explore in a population-based sample whether the relation between leptin and CRP is independent of obesity level and whether genetic causes of CRP elevation contribute to leptin levels.
Design: This was a population-based study including 1862 young adults (971 women; 891 men) aged 24-39 yr.