A Study on the Radiation Resistance Performance of an AlO Composite Tritium Permeation Barrier and Zirconium-Based Tritium-Absorbing Materials.

The permeation of tritium from secondary neutron source rods in nuclear power plants presents a significant and unavoidable safety concern both for internal equipment and the external environment. This study primarily explores two feasible strategies for tritium permeation barriers: coating stainless steel surfaces with tritium permeation barrier (TPB) materials and utilizing materials with excellent tritium absorption properties. Through external ion irradiation tests, a comparative analysis was conducted on the tritium permeation performance, morphology, and nanohardness changes in two tritium-resistant designs, specifically CrO/AlO composite coatings and a zirconium-based tritium-absorbing material under varying irradiation doses.

Effect of Mechanical Damage on Tritium Permeability Resistance of FeAl/AlO Coating on 316L Stainless Steel.

Depositing a tritium permeation barrier on the surface of materials is a key method for reducing tritium permeability. During actual operational processes, the surface of the tritium permeation barrier may experience mechanical damage, such as spalling and scratches. The hydrogen permeability resistance of the coating will degrade due to such forms of mechanical damage.

Association of phthalate exposure with type 2 diabetes and the mediating effect of oxidative stress: A case-control and computational toxicology study.

Phthalic acid esters (PAEs) are widely used as plasticizers and have been suggested to engender adverse effects on glucose metabolism. However, epidemiological data regarding the PAE mixture on type 2 diabetes (T2DM), as well as the mediating role of oxidative stress are scarce. This case-control study enrolled 206 T2DM cases and 206 matched controls in Guangdong Province, southern China.

Study on the Thermophysical Properties of 80% B Enrichment of BC.

In this paper, a specific type of Boron Carbide (BC) with a high enrichment of 80 ± 0.3 at% B was prepared as an absorbing material for control rods in nuclear reactors. The enrichment of B was achieved using a chemical exchange method, followed by obtaining boron carbide powder through a carbothermal reduction method.

TiO-PAA-SiO pearl chain blend modified polyvinylidene fluoride ultrafiltration membrane with excellent oil-water separation, anti fouling performance and durability.

In this work, a new type of composite nanoparticles, 'pearl chain', was developed by linking titanium dioxide and silicon dioxide by polyacrylic acid polymer chains, and the prepared TiO-PAA-SiO composite nanoparticles were analysed by SEM, Fourier transform infrared spectroscopy, x-ray photoelectron spectroscopy and thermogravimetric analysis, zeta potential, x-ray diffraction, etc. The success of this work was verified by the successful linking of TiO-PAA-SiO composite nanoparticles.TiO-PAA-SiO composite nanoparticles were analysed to verify the successful attachment of pearl chains.

Cervical lymph node metastasis of bladder cancer: a case report and review of literature.

Objective: To report an extremely rare case of bladder cancer patient with cervical lymph nodes, abdominal lymph nodes, and bone metastases at the same time.

Methods And Results: The case was investigated by follow-up and immunohistochemistry was used in the pathological part.

Result: The patient was diagnosed with bladder cancer (high-grade urothelial metastatic epithelial cell carcinoma) by pathology and immunohistochemistry after transurethral resection of bladder tumor (TURBT) and metastatic bladder cancer by pathology and immunohistochemistry after cervical lymph node aspiration due to neck lymph node enlargement 1 year later, and a CT of the chest and abdomen suggested that the patient also had abdominal lymph node and bone metastases.

Association of urinary iodine concentration with prediabetes/diabetes in adults: Analysis of the NHANES 2005-2016.

Background & Aims: Iodine is required for synthesizing thyroid hormones and regulating human metabolism. Iodine deficiency can lead to thyroid function abnormalities, which are closely associated with disturbances in glucose-insulin homeostasis. Research on the relationship between iodine and diabetes/prediabetes in adults was sparse and inconsistent.

Separation of oil vapour by polyether block amide composite membrane modified with porous materials.

The ability of membranes to separate oil vapour is affected by their permeance and selectivity. This study modifies polyether block amide (PEBA) composite membranes with a microporous zeolite, Silicalite-1, or a mesoporous zeolite, MCM-41. The results show that when PEBA composite membranes are modified with these zeolites, the selective layer of the composite membrane is coated more thinly, resulting in a higher flux of organic gas.

Graphene Oxide Modified Polyamide 66 Ultrafiltration Membranes with Enhanced Anti-Fouling Performance.

Improving the contamination resistance of membranes is one of the most effective ways to address the short service life of membranes. While preparing the membrane system structure, doping nanoparticles into the polymer matrix is beneficial to the preparation of high-performance membranes. To develop a new structure for membrane contamination protection, in this study, a novel asymmetric polyamide 66 composite ultrafiltration (UF) membrane was fabricated by incorporating different masses (ranging from zero to 0.

Axial Crystal Growth Evolution and Crystallization Characteristics of Bi-Continuous Polyamide 66 Membranes Prepared via the Cold Non-Solvent-Induced Phase Separation Technique.

Polyamide 66 microporous membranes were prepared by cold non-solvent-induced phase separation using polyamide 66-formic acid-propylene carbonate as a ternary membrane-forming system. The formed membranes exhibited a special bicontinuous structure consisting of interglued spherical crystals or interlocked bundles of microcrystalline aggregates. The variation of the microporous structure under the influence of preparation conditions, solvent, aging time, and polymer concentration affects the comprehensive performance of the membranes.

Transcriptomic Variations and Network Hubs Controlling Seed Size and Weight During Maize Seed Development.

To elucidate the mechanisms underlying seed development in maize, comprehensive RNA-seq analyses were conducted on Zhengdan1002 (ZD1002), Zhengdan958 (ZD958), and their parental lines during seven seed developmental stages. We found that gene expression levels were largely nonadditive in hybrids and that cis-only or trans × cis pattern played a large role in hybrid gene regulation during seed developmental stage. Weighted gene co-expression network (WGCNA) analysis showed that 36 modules were highly correlated ( = -0.

A brief review and case report of urothelial carcinoma and metachronous leiomyosarcoma of the bladder at the same anatomic region.

One patient with bladder leiomyosarcoma and urothelial carcinoma is very rare. Only 10 cases have been reported in the literature. A 70-year-old patient was admitted due to bladder tumor.

The association of aldehydes exposure with diabetes mellitus in US population: NHANES 2013-2014.

Background: The association of mixed aldehydes exposure with diabetes remains unclear.

Objective: We aimed to explore associations between serum aldehydes concentration and diabetes.

Methods: We analyzed associations between aldehydes and diabetes using data from 1795 participants in the National Health and Nutrition Examination Survey (NHANES) from 2013 to 2014 by multiple logistic regression models.

polysaccharides attenuate cardiovascular oxidative stress injury by enhancing the Keap1/Nrf2 signaling pathway in exhaustive exercise rats.

Moderate exercise is beneficial to physical and mental health. When the amount of exercise and exercise intensity exceeds a certain limit and reaches the state of exhaustion, oxidative stress levels in the body increase, which can lead to oxidative stress‑associated damage. polysaccharide (LBP) is one of the primary active ingredients extracted from wolfberry.

The predictive value of the ratio of the product of neutrophils and hemoglobin to lymphocytes in non-muscular invasive bladder cancer patients with postoperative recurrence.

Purpose: The purpose of this study was to explore the predictive value of the ratio of the product of neutrophils and hemoglobin to lymphocytes (NHL) in patients with non-muscular invasive bladder cancer (NMIBC).

Materials And Methods: We retrospectively collected clinical and pathological data of patients with NMIBC who underwent transurethral resection of bladder tumor (TURBT) at our hospital between 2013 and 2018. The ratio of neutrophils to lymphocytes (NLR), the Systemic Immune Inflammation Index (SII), and NHL were obtained based on routine blood settlement within a week before surgery.

[Betaine induces apoptosis of C4-2B prostate cancer cells via inhibiting PI3K/AKT/NF-κB signaling pathway].

Objective To investigate the inhibitory effect of betaine (BET) on the proliferation of C4-2B prostate cancer cells and its possible mechanism. Methods C4-2B cells were treated with 0, 100, 200, 400, 600, 800 mmol/L BET. CCK-8 assay was used to assess the cell proliferation, plate cloning formation assay to detect clone formation ability and flow cytometry to evaluate cell apoptosis, and the cell morphological alteration was observed by microscopy.

The meta-analysis of the effect of 68Ga-PSMA-PET/CT diagnosis of prostatic cancer compared with bone scan.

Background: 68Ga-PSMA-PET/CT (positron emission tomography/computed tomography) is a promising method for prostate cancer (PC) detection. However, the ability of 68Ga-PSMA-PET/CT to detect malignant bone lesions, and whether this method is superior to the existing bone imaging methods are still lack of systematic analysis.

Purpose: To evaluate the value of 68Ga-PSMA-PET/CT and bone scan in clinical diagnosis of prostatic cancer from the perspective of evidence-based medicine.

Effects of norepinephrine on colonic tight junction protein expression during heat stress.

Stress induced by changes in the internal or external environment in humans and animals leads to intestinal epithelial damage, in a manner that is associated with impaired intestinal barrier function. However, the role of the stress hormone norepinephrine (NE) in impairments in barrier function remains poorly understood. In the present study, a rat heat-exposed model was used to observe changes in the tight junction proteins Occludin and zonula occludens-1 (ZO-1), in addition to those in protease-activated receptor 2 (PAR-2) and transient receptor potential ankyrin 1 channel (TRPA1) in colon.

LncRNA XIST modulates 5-hydroxytrytophan-induced visceral hypersensitivity by epigenetic silencing of the SERT gene in mice with diarrhea-predominant IBS.

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a prevalent gastrointestinal disorder with a high incidence in children. The role of long non-coding RNAs (lncRNAs) in gastrointestinal diseases has been previously highlighted. Nevertheless, the underlying regulatory mechanism of lncRNA X inactivate-specific transcript (XIST) in IBS-D requires further studies.

Homocysteine accelerates atherosclerosis by inhibiting scavenger receptor class B member1 via DNMT3b/SP1 pathway.

Homocysteine (Hcy) is an independent risk factor for atherosclerosis, which is characterized by lipid accumulation in the atherosclerotic plaque. Increasing evidence supports that as the main receptor of high-density lipoprotein, scavenger receptor class B member 1 (SCARB1) is protective against atherosclerosis. However, the underlying mechanism regarding it in Hcy-mediated atherosclerosis remains unclear.

Role of EGFR/ErbB2 and PIK/AKT/e-NOS in Ameliorating Endothelial Dysfunction Induced by Oxidative Stress.

(LBP) are the major ingredients of . In this study, we investigated the role of LBP in endothelial dysfunction induced by oxidative stress and the underlying mechanisms using thoracic aortic endothelial cells of rat (RAECs) as a model. We found that Ang II inhibits cell viability of RAECs with 10mol/L of Ang II treatment for 24h most potential (), the level of reactive oxygen species (ROS) is increased by Ang II treatment (), and the expression of Occludin and Zonula occludens-1 (ZO-1) is decreased by Ang II treatment ().

Protective functions of Lycium barbarum polysaccharides in HO-injured vascular endothelial cells through anti-oxidation and anti-apoptosis effects.

Cell injury in the cardiovascular endothelia caused by oxidative stress is among the major inducers of endothelium dysfunction and serves an important role in initiating cardiovascular diseases (CVDs). Therefore, protecting and improving the normal function of endothelial cells are considered key measures against CVDs. As a traditional Chinese medicinal component, is regarded to have high medicinal value.

Association of Polymorphisms in miRNA Processing Genes With Type 2 Diabetes Mellitus and Its Vascular Complications in a Southern Chinese Population.

To evaluate the potential association between the genetic variants in miRNA processing genes (, and ) and susceptibility to type 2 diabetes mellitus (T2DM) and its vascular complications, as well as to further investigate their interaction with environmental factors in type 2 diabetes. We conducted a case-control study in genotyping of five polymorphic loci, including rs14035, rs11077, rs13078, rs3742330, and rs784567, in miRNA processing genes to explore the risk factors for T2DM and diabetic vascular complications. Haplotype analyses, interactions of gene-gene and interactions of gene-environment were performed too.

Association Analysis of NLRP3 Inflammation-Related Gene Promotor Methylation as Well as Mediating Effects on T2DM and Vascular Complications in a Southern Han Chinese Population.

To explore the association between the methylation levels in the promoter regions of the NLRP3, AIM2, and ASC genes and T2DM and its vascular complications in a Southern Han Chinese population and further analyze their interaction and mediating effects with environmental factors in T2DM. A case-control study was used to determine the association between population characteristics, the methylation level in the promoter region of the NLRP3, AIM2, and ASC genes and T2DM and vascular complications. A mediating effect among genes-environment-T2DM and the interaction of gene-gene or gene-environment factors was explored.