Multiple studies demonstrate the existence of attenuated neutralizing activity to the Omicron variants in the original SARS-CoV-2 strain vaccinated population undergoing breakthrough infection, which reflects a phenomenon of immune imprinting in humoral immunity. Herein, through designing spike protein peptide pools from four Omicron subvariants and the wild type (WT) counterpart, we intended to determine antiviral T cell immunoreactivity in Omicron-infected COVID-19 patients with or without previous vaccination. We have demonstrated that IFN-γ producing cells against the Omicron subvariants-derived peptide pools were significantly less than those against WT counterpart peptide pools in the Omicron BA.
View Article and Find Full Text PDFIntroduction: Sweetpotato (Ipomoea batatas (L.) Lam.) is a genetically intricate hexaploid crop.
View Article and Find Full Text PDFSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes a variety of clinical manifestations, many of which originate from altered immune responses, either locally or systemically. Immune cell cross-talk occurs mainly in lymphoid organs. However, systemic cell interaction specific to coronavirus disease 2019 has not been well characterized.
View Article and Find Full Text PDFExcessive oxidative stress and NLRP3 inflammasome activation are considered the main drivers of inflammatory bowel disease (IBD), and inhibition of inflammasomes ameliorates clinical symptoms and morphological manifestations of IBD. Herein, we examined the roles of NLRP3 activation in IBD and modulation of NLRP3 by sulforaphane (SFN), a compound with multiple pharmacological activities that is extracted from cruciferous plants. To simulate human IBD, we established a mouse colitis model by administering dextran sodium sulfate in the drinking water.
View Article and Find Full Text PDFObjectives: To investigate how BBIBP-CorV vaccination affecting antibody responses upon heterologous Omicron infection.
Methods: 440 Omicron-infected patients were recruited in this study. Antibodies targeting SARS-CoV-2 spike protein receptor binding domain (RBD) and nucleoprotein of both wild-type (WT) and Omicron were detected by ELISA.
Background: Plant carotenoids are essential for human health, having wide uses in dietary supplements, food colorants, animal feed additives, and cosmetics. With the increasing demand for natural carotenoids, plant carotenoids have gained great interest in both academic and industry research worldwide. Orange-fleshed sweetpotato (Ipomoea batatas) enriched with carotenoids is an ideal feedstock for producing natural carotenoids.
View Article and Find Full Text PDFCrown roots are the main components of the fibrous root system in cereal crops and play critical roles in plant adaptation; however, the molecular mechanisms underlying their formation in wheat (Triticum aestivum) have not been fully elucidated. In this study, we identified a wheat basic helix-loop-helix (bHLH) protein, TabHLH123, that interacts with the essential regulator of crown root initiation, MORE ROOT in wheat (TaMOR). TabHLH123 is expressed highly in shoot bases and roots.
View Article and Find Full Text PDFB-box (BBX) which are a class of zinc finger transcription factors, play an important role in regulating of photoperiod, photomorphogenesis, and biotic and abiotic stresses in plants. However, there are few studies on the involvement of BBX transcription factors in response to abiotic stresses in sweet potato. In this paper, we cloned the DNA and promoter sequences of .
View Article and Find Full Text PDFComput Intell Neurosci
October 2022
The development of remote sensing technology has passed an effective means for forest resource management and monitoring, but remote sensing technology is limited by sensor hardware equipment, and the quality of remote sensing image data is low, which is difficult to meet the needs of forest resource change monitoring. This paper presents a remote sensing image classification method based on the combination of the SSIF algorithm and wavelet denoising. Forest information is extracted from PALSAR/PALSAR-2 radar remote sensing data.
View Article and Find Full Text PDFSalt stress has a serious impact on normal plant growth and yield. Carotenoid cleavage dioxygenase (CCD) degrades carotenoids to produce apocarotenoids, which are involved in plant responses to biotic and abiotic stresses. This study shows that the expression of sweet potato was significantly induced by salt and dehydration stress.
View Article and Find Full Text PDFThis article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).
View Article and Find Full Text PDFDrought stress frequently occurs, which seriously restricts the production of wheat ( L.). Leaf rolling is a typical physiological phenomenon of plants during drought stress.
View Article and Find Full Text PDFFor a long time, forestry management has often focused on the protection of species diversity, and mistakenly believed that protecting species diversity protects genetic diversity. Therefore, research that integrates community ecology and population genetics has become important because it can help elucidate whether the targets for protecting specific and genetic diversity are congruent. In this study, we have emphasized the impact of the community on the population because no previous studies have considered the community composition of a place .
View Article and Find Full Text PDFPurple-fleshed sweetpotato (PFSP) accumulates high amounts of anthocyanins that are beneficial to human health. Although biosynthesis of such secondary metabolites has been well studied in aboveground organs of many plants, the mechanisms underlying anthocyanin accumulation in underground tuberous roots of sweetpotato are less understood. To identify genes and metabolites involved in anthocyanin accumulation in sweetpotato, we performed comparative transcriptomic and metabolomic analysis of (PFSP) and white-fleshed sweetpotato (WFSP).
View Article and Find Full Text PDFSweetpotato (Ipomoea batatas. L) is an important food crop, harvested for its nutrient-rich tuberous roots. Drought and salt stresses are two major factors limiting the sweetpotato production.
View Article and Find Full Text PDFBackground: Compared with white-fleshed sweetpotato (WFSP), purple-fleshed sweetpotato (PFSP) is a desirable resource for functional food development because of the abundant anthocyanin accumulation in its tuberous roots. Some studies have shown that the expression regulation mediated by miRNA plays an important role in anthocyanin biosynthesis in plants. However, few miRNAs and their corresponding functions related to anthocyanin biosynthesis in tuberous roots of sweetpotato have been known.
View Article and Find Full Text PDFJ Sci Food Agric
April 2016
Background: Northward expansion of winter wheat is an efficient means to improve crop yield and quality in many countries. However, inadequate cold hardiness restricts the northward expansion of winter wheat. This study aimed to investigate cold adaption of different wheat varieties and underlying physiological mechanism.
View Article and Find Full Text PDFCalreticulin (CRT) is a key Ca2+-binding protein mainly resident in the endoplasmic reticulum (ER), which is highly conserved and extensively expressed in all eukaryotic organisms investigated. The protein plays important roles in a variety of cellular processes including Ca2+ signaling and protein folding. Although calreticulin has been well characterized in mammalian systems, increased investigations have demonstrated that plant CRTs have a number of specific properties different from their animal counterparts.
View Article and Find Full Text PDFMicroRNAs (miRNAs), an endogenous type of small RNAs of approximately 22 nucleotides (nt), have long resided in the cells of plants and animals including humans, constituting an ancient pathway of gene regulation in eukaryotes. They have a simple structure in their mature form but carry enormous information that may regulate up to 90% of the human transcriptome. Furthermore, the multi-facets of a miRNA are tightly associated with diverse cellular proteins that make it broadly connected to various physiological and pathological processes.
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